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Triple visual hemifield maps in a case of optic chiasm hypoplasia

Ahmadi, Khazar LU ; Fracasso, Alessio ; Puzniak, Robert J. ; Gouws, Andre D. ; Yakupov, Renat ; Speck, Oliver ; Kaufmann, Joern ; Pestilli, Franco ; Dumoulin, Serge O. and Morland, Antony B. , et al. (2020) In NeuroImage 215.
Abstract

In humans, each hemisphere comprises an overlay of two visuotopic maps of the contralateral visual field, one from each eye. Is the capacity of the visual cortex limited to these two maps or are plastic mechanisms available to host more maps? We determined the cortical organization of the visual field maps in a rare individual with chiasma hypoplasia, where visual cortex plasticity is challenged to accommodate three hemifield maps. Using high-resolution fMRI at 7T and diffusion-weighted MRI at 3T, we found three hemiretinal inputs, instead of the normal two, to converge onto the left hemisphere. fMRI-based population receptive field mapping of the left V1–V3 at 3T revealed three superimposed hemifield representations in the left visual... (More)

In humans, each hemisphere comprises an overlay of two visuotopic maps of the contralateral visual field, one from each eye. Is the capacity of the visual cortex limited to these two maps or are plastic mechanisms available to host more maps? We determined the cortical organization of the visual field maps in a rare individual with chiasma hypoplasia, where visual cortex plasticity is challenged to accommodate three hemifield maps. Using high-resolution fMRI at 7T and diffusion-weighted MRI at 3T, we found three hemiretinal inputs, instead of the normal two, to converge onto the left hemisphere. fMRI-based population receptive field mapping of the left V1–V3 at 3T revealed three superimposed hemifield representations in the left visual cortex, i.e. two representations of opposing visual hemifields from the left eye and one right hemifield representation from the right eye. We conclude that developmental plasticity including the re-wiring of local intra- and cortico-cortical connections is pivotal to support the coexistence and functioning of three hemifield maps within one hemisphere.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
DWI, fMRI, Optic chiasm, Plasticity, Retinotopy, Visual cortex
in
NeuroImage
volume
215
article number
116822
publisher
Elsevier
external identifiers
  • pmid:32276070
  • scopus:85083344298
ISSN
1053-8119
DOI
10.1016/j.neuroimage.2020.116822
language
English
LU publication?
yes
id
12451148-e200-4259-aed1-3646d619ec2c
date added to LUP
2020-04-28 10:30:21
date last changed
2024-03-04 17:52:50
@article{12451148-e200-4259-aed1-3646d619ec2c,
  abstract     = {{<p>In humans, each hemisphere comprises an overlay of two visuotopic maps of the contralateral visual field, one from each eye. Is the capacity of the visual cortex limited to these two maps or are plastic mechanisms available to host more maps? We determined the cortical organization of the visual field maps in a rare individual with chiasma hypoplasia, where visual cortex plasticity is challenged to accommodate three hemifield maps. Using high-resolution fMRI at 7T and diffusion-weighted MRI at 3T, we found three hemiretinal inputs, instead of the normal two, to converge onto the left hemisphere. fMRI-based population receptive field mapping of the left V1–V3 at 3T revealed three superimposed hemifield representations in the left visual cortex, i.e. two representations of opposing visual hemifields from the left eye and one right hemifield representation from the right eye. We conclude that developmental plasticity including the re-wiring of local intra- and cortico-cortical connections is pivotal to support the coexistence and functioning of three hemifield maps within one hemisphere.</p>}},
  author       = {{Ahmadi, Khazar and Fracasso, Alessio and Puzniak, Robert J. and Gouws, Andre D. and Yakupov, Renat and Speck, Oliver and Kaufmann, Joern and Pestilli, Franco and Dumoulin, Serge O. and Morland, Antony B. and Hoffmann, Michael B.}},
  issn         = {{1053-8119}},
  keywords     = {{DWI; fMRI; Optic chiasm; Plasticity; Retinotopy; Visual cortex}},
  language     = {{eng}},
  month        = {{07}},
  publisher    = {{Elsevier}},
  series       = {{NeuroImage}},
  title        = {{Triple visual hemifield maps in a case of optic chiasm hypoplasia}},
  url          = {{http://dx.doi.org/10.1016/j.neuroimage.2020.116822}},
  doi          = {{10.1016/j.neuroimage.2020.116822}},
  volume       = {{215}},
  year         = {{2020}},
}