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Bioethical considerations for human nutrigenomics

Bergmann, Manuela M.; Görman, Ulf LU and Mathers, John C. (2008) In Annual Review of Nutrition 28. p.447-467
Abstract
This article gives an overview of the ethical issues in nutrigenomics; research and personalized nutrition. The principles of research ethics, i.e., autonomy, beneficence, nonmalfeasance, and justice, are challenged by rapidly growing cross-border research activities utilizing existing and upcoming biobanks for studies of the interaction of genes with diet on risk of common diseases. We highlight the ethical issues, some unresolved, in international collaborative projects of which researchers should be aware. Personalized nutrition (tailoring diet on the basis of genotype) is one possible application of nutrigenomics research. However, until the scientific evidence concerning diet-gene interactions is much more robust, the provision of... (More)
This article gives an overview of the ethical issues in nutrigenomics; research and personalized nutrition. The principles of research ethics, i.e., autonomy, beneficence, nonmalfeasance, and justice, are challenged by rapidly growing cross-border research activities utilizing existing and upcoming biobanks for studies of the interaction of genes with diet on risk of common diseases. We highlight the ethical issues, some unresolved, in international collaborative projects of which researchers should be aware. Personalized nutrition (tailoring diet on the basis of genotype) is one possible application of nutrigenomics research. However, until the scientific evidence concerning diet-gene interactions is much more robust, the provision of personalized dietary advice on the basis of specific genotype remains questionable. From the ethical and social perspective, nutrigenomics offers significant opportunities to improve public health by enhancing understanding of the mechanisms through which diet can be used to reduce the risk of common polygenic diseases. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
personalized nutrition, human studies, ethics, nutrigenomics
in
Annual Review of Nutrition
volume
28
pages
447 - 467
publisher
Annual Reviews
external identifiers
  • wos:000259084300024
  • scopus:51149098095
ISSN
0199-9885
DOI
10.1146/annurev.nutr.28.061807.155344
language
English
LU publication?
yes
id
deb9b1e0-b18f-4c30-bcf8-d1ac500c3512 (old id 1247108)
date added to LUP
2008-11-11 15:33:00
date last changed
2017-01-15 03:41:48
@article{deb9b1e0-b18f-4c30-bcf8-d1ac500c3512,
  abstract     = {This article gives an overview of the ethical issues in nutrigenomics; research and personalized nutrition. The principles of research ethics, i.e., autonomy, beneficence, nonmalfeasance, and justice, are challenged by rapidly growing cross-border research activities utilizing existing and upcoming biobanks for studies of the interaction of genes with diet on risk of common diseases. We highlight the ethical issues, some unresolved, in international collaborative projects of which researchers should be aware. Personalized nutrition (tailoring diet on the basis of genotype) is one possible application of nutrigenomics research. However, until the scientific evidence concerning diet-gene interactions is much more robust, the provision of personalized dietary advice on the basis of specific genotype remains questionable. From the ethical and social perspective, nutrigenomics offers significant opportunities to improve public health by enhancing understanding of the mechanisms through which diet can be used to reduce the risk of common polygenic diseases.},
  author       = {Bergmann, Manuela M. and Görman, Ulf and Mathers, John C.},
  issn         = {0199-9885},
  keyword      = {personalized nutrition,human studies,ethics,nutrigenomics},
  language     = {eng},
  pages        = {447--467},
  publisher    = {Annual Reviews},
  series       = {Annual Review of Nutrition},
  title        = {Bioethical considerations for human nutrigenomics},
  url          = {http://dx.doi.org/10.1146/annurev.nutr.28.061807.155344},
  volume       = {28},
  year         = {2008},
}