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Liquid ionization chamber calibrated gel dosimetry in conformal stereotactic radiotherapy of brain lesions

Bjoreland, Anders ; Lindvall, Peter ; Karlsson, Anna LU ; Gustafsson, Helen LU ; Bäck, Sven LU ; Karlsson, Mikael and Bergenheim, Tommy A. (2008) In Acta Oncologica 47(6). p.1099-1109
Abstract
Hypofractionated conformal stereotactic radiotherapy (HCSRT) is an established method of treating brain lesions such as arteriovenous malformations (AVMs) and brain metastases. The aim of this study was to investigate the reliability of treatment plans in the terms of dose distribution and absorbed dose for HCSRT. Methods and materials. Treatment plans for three different clinical intracerebral targets, AVMs, were transferred to a CT study of a spherical water filled phantom simulating the human head and recalculated for the phantom geometry using a standard treatment planning system utilizing a pencil beam algorithm for dose calculation. The calculated absorbed dose, relative three dimensional (3D) dose distribution and dose conformity... (More)
Hypofractionated conformal stereotactic radiotherapy (HCSRT) is an established method of treating brain lesions such as arteriovenous malformations (AVMs) and brain metastases. The aim of this study was to investigate the reliability of treatment plans in the terms of dose distribution and absorbed dose for HCSRT. Methods and materials. Treatment plans for three different clinical intracerebral targets, AVMs, were transferred to a CT study of a spherical water filled phantom simulating the human head and recalculated for the phantom geometry using a standard treatment planning system utilizing a pencil beam algorithm for dose calculation. The calculated absorbed dose, relative three dimensional (3D) dose distribution and dose conformity were investigated using gel dosimetry normalized to liquid ionization chamber (LIC) measurements. Results. The measured absorbed dose to the dose reference point was found to be within 2% of the calculated dose for all three targets. The measured dose distribution was found to be within 3% and 2 mm of the calculated dose for more than 93% of all points in the target volume for all three targets. Conclusions. The results show that the investigated standard treatment planning system can correctly predict the absorbed dose and dose distribution in different types of intracerebral targets and that the treatment can be delivered according to the plan. (Less)
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Oncologica
volume
47
issue
6
pages
1099 - 1109
publisher
Taylor & Francis
external identifiers
  • wos:000258905100015
  • scopus:51149090403
  • pmid:18607837
ISSN
1651-226X
DOI
10.1080/02841860801888781
language
English
LU publication?
yes
id
c8f9af28-f1ab-4a7d-929a-b5cf02d1b48a (old id 1247886)
date added to LUP
2016-04-01 13:04:03
date last changed
2022-01-27 17:06:34
@article{c8f9af28-f1ab-4a7d-929a-b5cf02d1b48a,
  abstract     = {{Hypofractionated conformal stereotactic radiotherapy (HCSRT) is an established method of treating brain lesions such as arteriovenous malformations (AVMs) and brain metastases. The aim of this study was to investigate the reliability of treatment plans in the terms of dose distribution and absorbed dose for HCSRT. Methods and materials. Treatment plans for three different clinical intracerebral targets, AVMs, were transferred to a CT study of a spherical water filled phantom simulating the human head and recalculated for the phantom geometry using a standard treatment planning system utilizing a pencil beam algorithm for dose calculation. The calculated absorbed dose, relative three dimensional (3D) dose distribution and dose conformity were investigated using gel dosimetry normalized to liquid ionization chamber (LIC) measurements. Results. The measured absorbed dose to the dose reference point was found to be within 2% of the calculated dose for all three targets. The measured dose distribution was found to be within 3% and 2 mm of the calculated dose for more than 93% of all points in the target volume for all three targets. Conclusions. The results show that the investigated standard treatment planning system can correctly predict the absorbed dose and dose distribution in different types of intracerebral targets and that the treatment can be delivered according to the plan.}},
  author       = {{Bjoreland, Anders and Lindvall, Peter and Karlsson, Anna and Gustafsson, Helen and Bäck, Sven and Karlsson, Mikael and Bergenheim, Tommy A.}},
  issn         = {{1651-226X}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{1099--1109}},
  publisher    = {{Taylor & Francis}},
  series       = {{Acta Oncologica}},
  title        = {{Liquid ionization chamber calibrated gel dosimetry in conformal stereotactic radiotherapy of brain lesions}},
  url          = {{http://dx.doi.org/10.1080/02841860801888781}},
  doi          = {{10.1080/02841860801888781}},
  volume       = {{47}},
  year         = {{2008}},
}