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Frontotemporal dementia - a clinically complex diagnosis

Rosness, Tor Atle; Haugen, Per Kristian; Passant, Ulla LU and Engedal, Knut (2008) In International Journal of Geriatric Psychiatry 23(8). p.837-842
Abstract
Objective To compare the time taken to establish a clinical diagnosis of Frontotemporal dementia (FTD) relative to a diagnosis of early onset Alzheimer's dementia (AD). Methods The data came from 89 patients under the age of 65 years, 52 of whom met the Manchester-Lund criteria for Frontotemporal dementia; 20 of these came from Lund University Hospital in Sweden. The other 32 patients with FTD along with 37 subjects who fulfilled the ICD-10 criteria for early onset Alzheimer's disease were recruited from four memory clinics and two neurology departments in Norway. Results For FTD patients in Norway it took 59.2 months (SD 36.1) from the onset of illness until a clinical FTD diagnosis was made. The corresponding time period for FTD patients... (More)
Objective To compare the time taken to establish a clinical diagnosis of Frontotemporal dementia (FTD) relative to a diagnosis of early onset Alzheimer's dementia (AD). Methods The data came from 89 patients under the age of 65 years, 52 of whom met the Manchester-Lund criteria for Frontotemporal dementia; 20 of these came from Lund University Hospital in Sweden. The other 32 patients with FTD along with 37 subjects who fulfilled the ICD-10 criteria for early onset Alzheimer's disease were recruited from four memory clinics and two neurology departments in Norway. Results For FTD patients in Norway it took 59.2 months (SD 36.1) from the onset of illness until a clinical FTD diagnosis was made. The corresponding time period for FTD patients in Sweden is 49.5 months (SD 24.5) and for AD patients in Norway 39.1 months (SD 19.9). The time from the first visit to a medical doctor until a diagnosis was made for the FTD patients in Norway was 34.5 months (SD 22.6), for the Swedish FTD patients 23.1 months (SD 22.4) and for the AD patients 25.9 months (SD 13.1). In all, 71% of FTD patients and 30% of AD patients initially received a non-dementia diagnosis. Conclusion More knowledge about early presenting cognitive and behavioural signs of FTD is needed in both primary and secondary health care to reduce the time period needed to establish a clinical diagnosis of FTD. Copyright (C) 2008 John Wiley & Sons, Ltd. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
diagnosis, dementia, Alzheimer's, frontotemporal, early onset, symptoms, clinical
in
International Journal of Geriatric Psychiatry
volume
23
issue
8
pages
837 - 842
publisher
John Wiley and Sons Ltd
external identifiers
  • wos:000258427800010
  • scopus:50249173823
ISSN
1099-1166
DOI
10.1002/gps.1992
language
English
LU publication?
yes
id
3da21bdf-c0cf-49a2-9043-50177b003e66 (old id 1252838)
date added to LUP
2008-11-17 14:48:08
date last changed
2017-07-23 03:39:57
@article{3da21bdf-c0cf-49a2-9043-50177b003e66,
  abstract     = {Objective To compare the time taken to establish a clinical diagnosis of Frontotemporal dementia (FTD) relative to a diagnosis of early onset Alzheimer's dementia (AD). Methods The data came from 89 patients under the age of 65 years, 52 of whom met the Manchester-Lund criteria for Frontotemporal dementia; 20 of these came from Lund University Hospital in Sweden. The other 32 patients with FTD along with 37 subjects who fulfilled the ICD-10 criteria for early onset Alzheimer's disease were recruited from four memory clinics and two neurology departments in Norway. Results For FTD patients in Norway it took 59.2 months (SD 36.1) from the onset of illness until a clinical FTD diagnosis was made. The corresponding time period for FTD patients in Sweden is 49.5 months (SD 24.5) and for AD patients in Norway 39.1 months (SD 19.9). The time from the first visit to a medical doctor until a diagnosis was made for the FTD patients in Norway was 34.5 months (SD 22.6), for the Swedish FTD patients 23.1 months (SD 22.4) and for the AD patients 25.9 months (SD 13.1). In all, 71% of FTD patients and 30% of AD patients initially received a non-dementia diagnosis. Conclusion More knowledge about early presenting cognitive and behavioural signs of FTD is needed in both primary and secondary health care to reduce the time period needed to establish a clinical diagnosis of FTD. Copyright (C) 2008 John Wiley & Sons, Ltd.},
  author       = {Rosness, Tor Atle and Haugen, Per Kristian and Passant, Ulla and Engedal, Knut},
  issn         = {1099-1166},
  keyword      = {diagnosis,dementia,Alzheimer's,frontotemporal,early onset,symptoms,clinical},
  language     = {eng},
  number       = {8},
  pages        = {837--842},
  publisher    = {John Wiley and Sons Ltd},
  series       = {International Journal of Geriatric Psychiatry},
  title        = {Frontotemporal dementia - a clinically complex diagnosis},
  url          = {http://dx.doi.org/10.1002/gps.1992},
  volume       = {23},
  year         = {2008},
}