HIV pozitif beş olguda serebral toksoplazmozisin renkli kliniği : Pandora'nin kutusundan çikanlar
(2006) In Mikrobiyoloji bulteni 40(1-2). p.85-92- Abstract
In patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), the most common cause of focal intracranial lesion is Toxoplasma gondii infection. T. gondii encephalitis is an easily and effectively treatable disease, with promising outcomes. T. gondii has the potential to form a focal infection niche anywhere in the central nervous system, thus allowing for a colorful clinical picture. In this report, we attempted to present five HIV/AIDS cases with central nervous system toxoplasmosis demonstrating five different neurological presentations. The ages, gender and clinical findings of the patients who were admitted to our Infectious Diseases Clinics were as follows; 35 years old male patient... (More)
In patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), the most common cause of focal intracranial lesion is Toxoplasma gondii infection. T. gondii encephalitis is an easily and effectively treatable disease, with promising outcomes. T. gondii has the potential to form a focal infection niche anywhere in the central nervous system, thus allowing for a colorful clinical picture. In this report, we attempted to present five HIV/AIDS cases with central nervous system toxoplasmosis demonstrating five different neurological presentations. The ages, gender and clinical findings of the patients who were admitted to our Infectious Diseases Clinics were as follows; 35 years old male patient with delirium, 49 years old male patient with focal dystony, 32 years old female patient with facial paralysis and monoparalysis, 53 years old male patient with Wernicke syndrome, 32 years old male patient with epilepsy. Cerebral toxoplasmosis were diagnosed by clinical findings and imaging techniques. The patients were treated with trimetoprim-sulfametoxazol (TMP-SMZ) and haloperidol, only TMP-SMZ, clindamycin and daraprim, TMP-SMZ and levotiracetam, TMP-SMZ and phenytoin, respectively, with recovery in neurological and radiological symptoms. In conclusion, until proven otherwise, HIV/AIDS patients presenting with focal neurological complaints should be accepted as having central nervous system toxoplasmosis.
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- author
- Kurne, Asli ; Ozkaya, Gülşen LU ; Karlioğuz, Kader ; Shorbagi, Ali ; Ustaçelebi, Semsettin ; Karabudak, Rana and Unal, Serhat
- alternative title
- The colorful clinical spectrum of cerebral toxoplasmosis in five HIV positive cases : what comes out of Pandora's box?
- publishing date
- 2006-06-17
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Acquired Immunodeficiency Syndrome/complications, Adult, Delirium/parasitology, Dystonic Disorders/parasitology, Epilepsy/parasitology, Facial Paralysis/parasitology, Female, HIV Infections/complications, Humans, Male, Middle Aged, Toxoplasmosis, Cerebral/drug therapy, Wernicke Encephalopathy/parasitology
- in
- Mikrobiyoloji bulteni
- volume
- 40
- issue
- 1-2
- pages
- 8 pages
- publisher
- Ankara Microbiology Society
- external identifiers
-
- scopus:39049195481
- pmid:16775962
- ISSN
- 0374-9096
- language
- Turkish
- LU publication?
- no
- id
- 125b5454-4f4a-4e6f-a1d9-f3feeaefd616
- alternative location
- http://www.mikrobiyolbul.org/managete/fu_folder/2006-01-02/2006-40-01-085-092.pdf
- date added to LUP
- 2019-06-30 00:55:17
- date last changed
- 2024-01-01 14:29:03
@article{125b5454-4f4a-4e6f-a1d9-f3feeaefd616,
abstract = {{<p>In patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), the most common cause of focal intracranial lesion is Toxoplasma gondii infection. T. gondii encephalitis is an easily and effectively treatable disease, with promising outcomes. T. gondii has the potential to form a focal infection niche anywhere in the central nervous system, thus allowing for a colorful clinical picture. In this report, we attempted to present five HIV/AIDS cases with central nervous system toxoplasmosis demonstrating five different neurological presentations. The ages, gender and clinical findings of the patients who were admitted to our Infectious Diseases Clinics were as follows; 35 years old male patient with delirium, 49 years old male patient with focal dystony, 32 years old female patient with facial paralysis and monoparalysis, 53 years old male patient with Wernicke syndrome, 32 years old male patient with epilepsy. Cerebral toxoplasmosis were diagnosed by clinical findings and imaging techniques. The patients were treated with trimetoprim-sulfametoxazol (TMP-SMZ) and haloperidol, only TMP-SMZ, clindamycin and daraprim, TMP-SMZ and levotiracetam, TMP-SMZ and phenytoin, respectively, with recovery in neurological and radiological symptoms. In conclusion, until proven otherwise, HIV/AIDS patients presenting with focal neurological complaints should be accepted as having central nervous system toxoplasmosis.</p>}},
author = {{Kurne, Asli and Ozkaya, Gülşen and Karlioğuz, Kader and Shorbagi, Ali and Ustaçelebi, Semsettin and Karabudak, Rana and Unal, Serhat}},
issn = {{0374-9096}},
keywords = {{Acquired Immunodeficiency Syndrome/complications; Adult; Delirium/parasitology; Dystonic Disorders/parasitology; Epilepsy/parasitology; Facial Paralysis/parasitology; Female; HIV Infections/complications; Humans; Male; Middle Aged; Toxoplasmosis, Cerebral/drug therapy; Wernicke Encephalopathy/parasitology}},
language = {{tur}},
month = {{06}},
number = {{1-2}},
pages = {{85--92}},
publisher = {{Ankara Microbiology Society}},
series = {{Mikrobiyoloji bulteni}},
title = {{HIV pozitif beş olguda serebral toksoplazmozisin renkli kliniği : Pandora'nin kutusundan çikanlar}},
url = {{http://www.mikrobiyolbul.org/managete/fu_folder/2006-01-02/2006-40-01-085-092.pdf}},
volume = {{40}},
year = {{2006}},
}