Expression of the novel gene Ened during mouse and Xenopus embryonic development.
(2008) In International Journal of Developmental Biology 52(8). p.1119-1122- Abstract
- We have recently identified 1110032E23Rik as a down-regulated target gene in Fgf receptor-signalling-deficient mouse embryoid bodies. Here, we present the expression pattern of this novel gene, designated Ened (Expressed in Nerve and Epithelium during Development), in mouse and Xenopus laevis embryos. Murine Ened transcripts were first seen at E9.5 in the heart and the gastrointestinal tract. At later stages of gestation, expression could be found in the floor plate, peripheral nervous system, lens epithelium, skin, midline dorsal aorta, lung, kidney and testis. In Xenopus, the expression of the Ened orthologue displayed common RNA distribution in several ectodermal and mesodermal tissues, but also distinct expression in locations... (More)
- We have recently identified 1110032E23Rik as a down-regulated target gene in Fgf receptor-signalling-deficient mouse embryoid bodies. Here, we present the expression pattern of this novel gene, designated Ened (Expressed in Nerve and Epithelium during Development), in mouse and Xenopus laevis embryos. Murine Ened transcripts were first seen at E9.5 in the heart and the gastrointestinal tract. At later stages of gestation, expression could be found in the floor plate, peripheral nervous system, lens epithelium, skin, midline dorsal aorta, lung, kidney and testis. In Xenopus, the expression of the Ened orthologue displayed common RNA distribution in several ectodermal and mesodermal tissues, but also distinct expression in locations including the brain, notochord and blood islands. We suggest that Ened might be a novel target gene of the Fgfr signalling pathway during embryonic development, and that its expression could be modulated by the basement membrane component laminin-111. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1261867
- author
- Gustafsson, Renata LU ; Strate, Ina LU ; Pera, Edgar LU and Durbeej-Hjalt, Madeleine LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- in
- International Journal of Developmental Biology
- volume
- 52
- issue
- 8
- pages
- 1119 - 1122
- publisher
- U B C Press
- external identifiers
-
- wos:000262153300013
- pmid:18956345
- scopus:61449530989
- pmid:18956345
- ISSN
- 1696-3547
- DOI
- 10.1387/ijdb.082700rm
- language
- English
- LU publication?
- yes
- id
- b556368e-1c9c-4cc7-ac1b-100921a2840b (old id 1261867)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/18956345?dopt=Abstract
- date added to LUP
- 2016-04-04 07:23:24
- date last changed
- 2022-01-29 02:05:51
@article{b556368e-1c9c-4cc7-ac1b-100921a2840b,
abstract = {{We have recently identified 1110032E23Rik as a down-regulated target gene in Fgf receptor-signalling-deficient mouse embryoid bodies. Here, we present the expression pattern of this novel gene, designated Ened (Expressed in Nerve and Epithelium during Development), in mouse and Xenopus laevis embryos. Murine Ened transcripts were first seen at E9.5 in the heart and the gastrointestinal tract. At later stages of gestation, expression could be found in the floor plate, peripheral nervous system, lens epithelium, skin, midline dorsal aorta, lung, kidney and testis. In Xenopus, the expression of the Ened orthologue displayed common RNA distribution in several ectodermal and mesodermal tissues, but also distinct expression in locations including the brain, notochord and blood islands. We suggest that Ened might be a novel target gene of the Fgfr signalling pathway during embryonic development, and that its expression could be modulated by the basement membrane component laminin-111.}},
author = {{Gustafsson, Renata and Strate, Ina and Pera, Edgar and Durbeej-Hjalt, Madeleine}},
issn = {{1696-3547}},
language = {{eng}},
number = {{8}},
pages = {{1119--1122}},
publisher = {{U B C Press}},
series = {{International Journal of Developmental Biology}},
title = {{Expression of the novel gene Ened during mouse and Xenopus embryonic development.}},
url = {{http://dx.doi.org/10.1387/ijdb.082700rm}},
doi = {{10.1387/ijdb.082700rm}},
volume = {{52}},
year = {{2008}},
}