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Smoking as a risk factor for myelodysplastic syndromes and acute myeloid leukemia and its relation to cytogenetic findings: A case-control study.

Björk, Jonas LU orcid ; Johansson, Bertil LU ; Broberg Palmgren, Karin LU orcid and Albin, Maria LU (2009) In Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis Nov 17. p.788-791
Abstract
In this case-control study, interview data on smoking habits were available for 179 de novo cases (116 with cytogenetic data) of acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Smoking habits were compared with a pooled set of population controls and hospital controls (diagnosed with malignant melanoma). Each pack-year of smoking increased the risk of MDS with 1.3% (95% CI 0.1-2.6%), corresponding to an estimated excess risk of 71% (95% CI 3-180%) for 40 pack-years. Associations between smoking and the specific aberrations -5/5q-, -7/7q-, and +8 in AML and MDS were indicated but the estimates were imprecise.
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis
volume
Nov 17
pages
788 - 791
publisher
Elsevier
external identifiers
  • wos:000265771600014
  • pmid:19019430
  • scopus:63349093481
ISSN
1873-5835
DOI
10.1016/j.leukres.2008.10.009
language
English
LU publication?
yes
id
b86b4786-67be-421a-9bb3-bee9fbab7876 (old id 1271323)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19019430?dopt=Abstract
date added to LUP
2016-04-04 08:41:31
date last changed
2025-01-06 01:20:45
@article{b86b4786-67be-421a-9bb3-bee9fbab7876,
  abstract     = {{In this case-control study, interview data on smoking habits were available for 179 de novo cases (116 with cytogenetic data) of acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Smoking habits were compared with a pooled set of population controls and hospital controls (diagnosed with malignant melanoma). Each pack-year of smoking increased the risk of MDS with 1.3% (95% CI 0.1-2.6%), corresponding to an estimated excess risk of 71% (95% CI 3-180%) for 40 pack-years. Associations between smoking and the specific aberrations -5/5q-, -7/7q-, and +8 in AML and MDS were indicated but the estimates were imprecise.}},
  author       = {{Björk, Jonas and Johansson, Bertil and Broberg Palmgren, Karin and Albin, Maria}},
  issn         = {{1873-5835}},
  language     = {{eng}},
  pages        = {{788--791}},
  publisher    = {{Elsevier}},
  series       = {{Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis}},
  title        = {{Smoking as a risk factor for myelodysplastic syndromes and acute myeloid leukemia and its relation to cytogenetic findings: A case-control study.}},
  url          = {{http://dx.doi.org/10.1016/j.leukres.2008.10.009}},
  doi          = {{10.1016/j.leukres.2008.10.009}},
  volume       = {{Nov 17}},
  year         = {{2009}},
}