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Long-term predictors of increased mortality risk in screened men with new hypertension; the Malmo preventive project.

Nilsson, Peter LU ; Engström, Gunnar LU and Hedblad, Bo LU (2008) In Journal of Hypertension 26(12). p.2288-2294
Abstract
OBJECTIVE: Regular blood pressure control has been advocated for early detection and treatment of patients with hypertension. We aimed to study whether long-term survival rate is related to socioeconomic circumstances and biological factors among middle-aged men with screened new hypertension. METHODS: Of the 22 444 men who attended a general health examination in Malmo, Sweden during 1974-1984, in total, 2033 had a systolic or diastolic blood pressure of at least 160 or 100 mmHg and were without treatment for hypertension. Mean age was 45.8 (SD: 5.3) years. All-cause mortality was studied in relation to smoking, diabetes, hyperlipidaemia, being overweight, marital status, problematic alcohol drinking, and occupation over a mean follow-up... (More)
OBJECTIVE: Regular blood pressure control has been advocated for early detection and treatment of patients with hypertension. We aimed to study whether long-term survival rate is related to socioeconomic circumstances and biological factors among middle-aged men with screened new hypertension. METHODS: Of the 22 444 men who attended a general health examination in Malmo, Sweden during 1974-1984, in total, 2033 had a systolic or diastolic blood pressure of at least 160 or 100 mmHg and were without treatment for hypertension. Mean age was 45.8 (SD: 5.3) years. All-cause mortality was studied in relation to smoking, diabetes, hyperlipidaemia, being overweight, marital status, problematic alcohol drinking, and occupation over a mean follow-up of 18.6 (3.6) years. RESULTS: Screened hypertension (>/=160/>/=100 mmHg) was significantly more common among men with low occupational level and among single men. Higher risk factor levels were associated with an adverse social background. Of the men with screened hypertension, 479 (24%) died during the follow-up, half of them from cardiovascular diseases. Compared with married men with normal blood pressure, married men with screened hypertension had a relative mortality risk of 1.5 (95% confidence interval = 1.3-1.7), whereas the relative risk for corresponding single men was 3.0 (2.6-3.4) adjusted for confounders. Among men with screened hypertension, marital status, systolic blood pressure at baseline, smoking, diabetes, hyperlipidaemia, and low occupation level (manual) remained significantly associated with total mortality in the multivariate analysis. CONCLUSION: Marital status contributes substantially to the survival prognosis for men with screened new hypertension. Systolic blood pressure at baseline and other known risk factors for atherosclerosis were also associated with increased mortality in this group. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Hypertension
volume
26
issue
12
pages
2288 - 2294
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000261404100008
  • pmid:19008707
  • scopus:59849105009
ISSN
1473-5598
DOI
10.1097/HJH.0b013e32831313b1
language
English
LU publication?
yes
id
164eff59-29d5-4015-9e5a-7c3e634ae2d3 (old id 1271452)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19008707?dopt=Abstract
date added to LUP
2008-12-04 15:28:26
date last changed
2017-01-01 07:42:25
@article{164eff59-29d5-4015-9e5a-7c3e634ae2d3,
  abstract     = {OBJECTIVE: Regular blood pressure control has been advocated for early detection and treatment of patients with hypertension. We aimed to study whether long-term survival rate is related to socioeconomic circumstances and biological factors among middle-aged men with screened new hypertension. METHODS: Of the 22 444 men who attended a general health examination in Malmo, Sweden during 1974-1984, in total, 2033 had a systolic or diastolic blood pressure of at least 160 or 100 mmHg and were without treatment for hypertension. Mean age was 45.8 (SD: 5.3) years. All-cause mortality was studied in relation to smoking, diabetes, hyperlipidaemia, being overweight, marital status, problematic alcohol drinking, and occupation over a mean follow-up of 18.6 (3.6) years. RESULTS: Screened hypertension (>/=160/>/=100 mmHg) was significantly more common among men with low occupational level and among single men. Higher risk factor levels were associated with an adverse social background. Of the men with screened hypertension, 479 (24%) died during the follow-up, half of them from cardiovascular diseases. Compared with married men with normal blood pressure, married men with screened hypertension had a relative mortality risk of 1.5 (95% confidence interval = 1.3-1.7), whereas the relative risk for corresponding single men was 3.0 (2.6-3.4) adjusted for confounders. Among men with screened hypertension, marital status, systolic blood pressure at baseline, smoking, diabetes, hyperlipidaemia, and low occupation level (manual) remained significantly associated with total mortality in the multivariate analysis. CONCLUSION: Marital status contributes substantially to the survival prognosis for men with screened new hypertension. Systolic blood pressure at baseline and other known risk factors for atherosclerosis were also associated with increased mortality in this group.},
  author       = {Nilsson, Peter and Engström, Gunnar and Hedblad, Bo},
  issn         = {1473-5598},
  language     = {eng},
  number       = {12},
  pages        = {2288--2294},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Journal of Hypertension},
  title        = {Long-term predictors of increased mortality risk in screened men with new hypertension; the Malmo preventive project.},
  url          = {http://dx.doi.org/10.1097/HJH.0b013e32831313b1},
  volume       = {26},
  year         = {2008},
}