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Water uptake and release from iodine-containing bone cement.

Kjellson, Fred LU ; Brudeli, B.; McCarthy, Ian LU and Lidgren, Lars LU (2004) In Journal of Biomedical Materials Research. Part A 71(2). p.292-298
Abstract
Water uptake and release characteristics of PMMA cement containing the water-soluble contrast media iohexol or iodixanol have been investigated. The water uptake study revealed that iohexol had the highest uptake of water (3.7%) and that iodixanol had an uptake close to that of Palacos(R) R (2.3% and 1.9%). The curves obtained showed the materials to follow classic diffusion theory, with an initial linearity with respect to t(1/2) making it possible to calculate the diffusion coefficients. This showed iohexol to have the lowest diffusion coefficient, Palacos(R) R the highest, and iodixanol close to that of Palacos(R) R. The release study showed that more iohexol than iodixanol was released from the bone cement; the long-term release was... (More)
Water uptake and release characteristics of PMMA cement containing the water-soluble contrast media iohexol or iodixanol have been investigated. The water uptake study revealed that iohexol had the highest uptake of water (3.7%) and that iodixanol had an uptake close to that of Palacos(R) R (2.3% and 1.9%). The curves obtained showed the materials to follow classic diffusion theory, with an initial linearity with respect to t(1/2) making it possible to calculate the diffusion coefficients. This showed iohexol to have the lowest diffusion coefficient, Palacos(R) R the highest, and iodixanol close to that of Palacos(R) R. The release study showed that more iohexol than iodixanol was released from the bone cement; the long-term release was above 25 mug/ml, for iohexol compared to slightly above 10 mug/mL for iodixanol. A muCT investigation showed that the risk of developing an observable radiolucent zone is negligible. (C) 2004 Wiley Periodicals, Inc. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
water uptake, water, release, poly(methyl methacrylate), absorption characteristics
in
Journal of Biomedical Materials Research. Part A
volume
71
issue
2
pages
292 - 298
publisher
John Wiley & Sons
external identifiers
  • pmid:15386486
  • wos:000224419000013
  • scopus:5444232124
ISSN
1552-4965
DOI
10.1002/jbm.a.30162
language
English
LU publication?
yes
id
ca77edb8-9923-43d0-80c7-0181cd633ccf (old id 127220)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15386486&dopt=Abstract
date added to LUP
2007-07-03 13:47:00
date last changed
2017-01-01 05:08:08
@article{ca77edb8-9923-43d0-80c7-0181cd633ccf,
  abstract     = {Water uptake and release characteristics of PMMA cement containing the water-soluble contrast media iohexol or iodixanol have been investigated. The water uptake study revealed that iohexol had the highest uptake of water (3.7%) and that iodixanol had an uptake close to that of Palacos(R) R (2.3% and 1.9%). The curves obtained showed the materials to follow classic diffusion theory, with an initial linearity with respect to t(1/2) making it possible to calculate the diffusion coefficients. This showed iohexol to have the lowest diffusion coefficient, Palacos(R) R the highest, and iodixanol close to that of Palacos(R) R. The release study showed that more iohexol than iodixanol was released from the bone cement; the long-term release was above 25 mug/ml, for iohexol compared to slightly above 10 mug/mL for iodixanol. A muCT investigation showed that the risk of developing an observable radiolucent zone is negligible. (C) 2004 Wiley Periodicals, Inc.},
  author       = {Kjellson, Fred and Brudeli, B. and McCarthy, Ian and Lidgren, Lars},
  issn         = {1552-4965},
  keyword      = {water uptake,water,release,poly(methyl methacrylate),absorption characteristics},
  language     = {eng},
  number       = {2},
  pages        = {292--298},
  publisher    = {John Wiley & Sons},
  series       = {Journal of Biomedical Materials Research. Part A},
  title        = {Water uptake and release from iodine-containing bone cement.},
  url          = {http://dx.doi.org/10.1002/jbm.a.30162},
  volume       = {71},
  year         = {2004},
}