Advanced

Intrinsic laryngeal muscles are spared from degeneration in the dy(3k)/dy(3k) mouse model of congenital muscular dystrophy type 1A.

Häger, Mattias LU and Durbeej-Hjalt, Madeleine LU (2009) In Muscle and Nerve 39(1). p.91-94
Abstract
Deficiency of laminin alpha2 chain leads to a severe form of congenital muscular dystrophy (MDC1A). Here, we analyzed whether the intrinsic laryngeal muscles (ILM) are spared in the dy(3K)/dy(3K) mouse model of complete laminin alpha2 chain absence. No muscle degeneration was evident; expression of various laminin chains was similar to that of limb muscles, and sustained integrin alpha7B expression was noted in laminin alpha2 chain-deficient ILM. We conclude that ILM are spared in MDC1A. Muscle Nerve 39: 91-94, 2009.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Muscle and Nerve
volume
39
issue
1
pages
91 - 94
publisher
John Wiley & Sons
external identifiers
  • wos:000262072100012
  • pmid:19086066
  • scopus:60549112579
ISSN
0148-639X
DOI
10.1002/mus.21209
language
English
LU publication?
yes
id
e4f339e0-02cb-4b8b-b889-689f330ddff3 (old id 1276158)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19086066?dopt=Abstract
date added to LUP
2009-01-09 11:58:22
date last changed
2017-01-01 07:29:43
@article{e4f339e0-02cb-4b8b-b889-689f330ddff3,
  abstract     = {Deficiency of laminin alpha2 chain leads to a severe form of congenital muscular dystrophy (MDC1A). Here, we analyzed whether the intrinsic laryngeal muscles (ILM) are spared in the dy(3K)/dy(3K) mouse model of complete laminin alpha2 chain absence. No muscle degeneration was evident; expression of various laminin chains was similar to that of limb muscles, and sustained integrin alpha7B expression was noted in laminin alpha2 chain-deficient ILM. We conclude that ILM are spared in MDC1A. Muscle Nerve 39: 91-94, 2009.},
  author       = {Häger, Mattias and Durbeej-Hjalt, Madeleine},
  issn         = {0148-639X},
  language     = {eng},
  number       = {1},
  pages        = {91--94},
  publisher    = {John Wiley & Sons},
  series       = {Muscle and Nerve},
  title        = {Intrinsic laryngeal muscles are spared from degeneration in the dy(3k)/dy(3k) mouse model of congenital muscular dystrophy type 1A.},
  url          = {http://dx.doi.org/10.1002/mus.21209},
  volume       = {39},
  year         = {2009},
}