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Developments in macromolecular drug delivery.

Belting, Mattias LU and Wittrup, Anders LU (2009) In Methods in Molecular Biology 480. p.1-10
Abstract
Macromolecular drugs hold great promise as novel therapeutics of several major disorders, such as cancer and cardiovascular disease. However, their use is limited by lack of efficient, safe, and specific delivery strategies. Successful development of such strategies requires interdisciplinary collaborations involving researchers with expertise on, e.g., polymer chemistry, cell biology, nanotechnology, systems biology, advanced imaging methods, and clinical medicine. This not only poses obvious challenges to the scientific community but also provides opportunities for the unexpected at the interface between different disciplines. This introductory chapter summarizes and gives references to studies on macromolecular delivery that should be... (More)
Macromolecular drugs hold great promise as novel therapeutics of several major disorders, such as cancer and cardiovascular disease. However, their use is limited by lack of efficient, safe, and specific delivery strategies. Successful development of such strategies requires interdisciplinary collaborations involving researchers with expertise on, e.g., polymer chemistry, cell biology, nanotechnology, systems biology, advanced imaging methods, and clinical medicine. This not only poses obvious challenges to the scientific community but also provides opportunities for the unexpected at the interface between different disciplines. This introductory chapter summarizes and gives references to studies on macromolecular delivery that should be of interest to a broad scientific audience involved in macromolecular drug synthesis as well as in vitro and in vivo drug delivery studies. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Methods in Molecular Biology
volume
480
pages
1 - 10
publisher
Springer
external identifiers
  • pmid:19085127
  • scopus:84934436463
ISSN
1940-6029
DOI
10.1007/978-1-59745-429-2_1
language
English
LU publication?
yes
id
0ec769e1-df7c-41da-9239-9f768bdcabd9 (old id 1276182)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19085127?dopt=Abstract
date added to LUP
2009-01-09 12:04:39
date last changed
2017-10-01 04:59:23
@article{0ec769e1-df7c-41da-9239-9f768bdcabd9,
  abstract     = {Macromolecular drugs hold great promise as novel therapeutics of several major disorders, such as cancer and cardiovascular disease. However, their use is limited by lack of efficient, safe, and specific delivery strategies. Successful development of such strategies requires interdisciplinary collaborations involving researchers with expertise on, e.g., polymer chemistry, cell biology, nanotechnology, systems biology, advanced imaging methods, and clinical medicine. This not only poses obvious challenges to the scientific community but also provides opportunities for the unexpected at the interface between different disciplines. This introductory chapter summarizes and gives references to studies on macromolecular delivery that should be of interest to a broad scientific audience involved in macromolecular drug synthesis as well as in vitro and in vivo drug delivery studies.},
  author       = {Belting, Mattias and Wittrup, Anders},
  issn         = {1940-6029},
  language     = {eng},
  pages        = {1--10},
  publisher    = {Springer},
  series       = {Methods in Molecular Biology},
  title        = {Developments in macromolecular drug delivery.},
  url          = {http://dx.doi.org/10.1007/978-1-59745-429-2_1},
  volume       = {480},
  year         = {2009},
}