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Screening for acrylate/methacrylate allergy in the baseline series: our experience in Sweden and Singapore

Goon, Anthony Teik-Jin; Bruze, Magnus LU ; Zimerson, Erik LU ; Goh, Chee-Leok; Koh, David Soo-Quee and Isaksson, Marléne LU (2008) In Contact Dermatitis 59(5). p.307-313
Abstract
Background: No studies to specifically determine the prevalence of contact allergy to acrylates/methacrylates in patch tested populations have been published. Objectives: To determine the prevalence of acrylate/methacrylate allergy in all patients tested to the baseline patch test series. Methods: Five acrylate/methacrylate allergens (2-hydroxyethyl methacrylate, methyl methacrylate, ethylene glycol dimethacrylate, triethylene glycol diacrylate, and 2-hydroxypropyl acrylate) were included in the baseline series for at least 2 years in Malmo and Singapore. Results: Thirty-eight patients in total had reacted to acrylate/methacrylate allergens in the baseline series during the study period in both populations. In Malmo, there were 26 (1.4%)... (More)
Background: No studies to specifically determine the prevalence of contact allergy to acrylates/methacrylates in patch tested populations have been published. Objectives: To determine the prevalence of acrylate/methacrylate allergy in all patients tested to the baseline patch test series. Methods: Five acrylate/methacrylate allergens (2-hydroxyethyl methacrylate, methyl methacrylate, ethylene glycol dimethacrylate, triethylene glycol diacrylate, and 2-hydroxypropyl acrylate) were included in the baseline series for at least 2 years in Malmo and Singapore. Results: Thirty-eight patients in total had reacted to acrylate/methacrylate allergens in the baseline series during the study period in both populations. In Malmo, there were 26 (1.4%) patients with positive patch tests to acrylate/methacrylate allergens, 14 of whom had relevant reactions. In Singapore, there were 12 (1.0%) patients with positive patch tests to acrylate/methacrylate allergens, but only 1 had relevant reactions. If we had not added acrylate/methacrylate allergens to the baseline series, we would not have patch tested 13/26 (50%) of the positive reactors in Malmo and 11/12 (92%) of the positive reactors in Singapore. The overall proportion of missed positive reactors would have been 24/38 (63%). Conclusions: The prevalence of acrylate/methacrylate allergy in our patch tested dermatitis populations is 1.4% in Malmo and 1.0% in Singapore. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
patch test, baseline series, allergic contact dermatitis, acrylates, screening
in
Contact Dermatitis
volume
59
issue
5
pages
307 - 313
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • wos:000260527800009
  • scopus:55149099860
ISSN
0105-1873
DOI
10.1111/j.1600-0536.2008.01440.x
language
English
LU publication?
yes
id
2d2edeb5-9455-4fa9-864f-c9e8a9c99d4a (old id 1283472)
date added to LUP
2009-02-10 11:25:18
date last changed
2017-08-27 03:51:31
@article{2d2edeb5-9455-4fa9-864f-c9e8a9c99d4a,
  abstract     = {Background: No studies to specifically determine the prevalence of contact allergy to acrylates/methacrylates in patch tested populations have been published. Objectives: To determine the prevalence of acrylate/methacrylate allergy in all patients tested to the baseline patch test series. Methods: Five acrylate/methacrylate allergens (2-hydroxyethyl methacrylate, methyl methacrylate, ethylene glycol dimethacrylate, triethylene glycol diacrylate, and 2-hydroxypropyl acrylate) were included in the baseline series for at least 2 years in Malmo and Singapore. Results: Thirty-eight patients in total had reacted to acrylate/methacrylate allergens in the baseline series during the study period in both populations. In Malmo, there were 26 (1.4%) patients with positive patch tests to acrylate/methacrylate allergens, 14 of whom had relevant reactions. In Singapore, there were 12 (1.0%) patients with positive patch tests to acrylate/methacrylate allergens, but only 1 had relevant reactions. If we had not added acrylate/methacrylate allergens to the baseline series, we would not have patch tested 13/26 (50%) of the positive reactors in Malmo and 11/12 (92%) of the positive reactors in Singapore. The overall proportion of missed positive reactors would have been 24/38 (63%). Conclusions: The prevalence of acrylate/methacrylate allergy in our patch tested dermatitis populations is 1.4% in Malmo and 1.0% in Singapore.},
  author       = {Goon, Anthony Teik-Jin and Bruze, Magnus and Zimerson, Erik and Goh, Chee-Leok and Koh, David Soo-Quee and Isaksson, Marléne},
  issn         = {0105-1873},
  keyword      = {patch test,baseline series,allergic contact dermatitis,acrylates,screening},
  language     = {eng},
  number       = {5},
  pages        = {307--313},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Contact Dermatitis},
  title        = {Screening for acrylate/methacrylate allergy in the baseline series: our experience in Sweden and Singapore},
  url          = {http://dx.doi.org/10.1111/j.1600-0536.2008.01440.x},
  volume       = {59},
  year         = {2008},
}