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Effects of a supplementary diet with specially processed cereals in patients with short bowel syndrome

Pagoldh, Maria; Eriksson, Anders; Heimtun, Erling; Kvifors, Eva; Sternby, Berit; Blomquist, Lars LU ; Lapidus, Annika; Suhr, Ole; Lange, Stefan and Karlbom, Urban, et al. (2008) In European Journal of Gastroenterology and Hepathology 20(11). p.1085-1093
Abstract
Objective Short bowel syndrome patients frequently experience impaired health-related quality of life. This syndrome is also associated with increased costs for the individuals concerned and the community. Intake of specially processed cereals has been demonstrated to decrease intestinal secretion. This study evaluates the effect of a supplementary diet with specially processed cereals compared with nonprocessed cereals. Methods This investigation is a randomized double-blind, cross-over multicentre prospective study of 26 intestinal resected out patients, considered as short bowel syndrome patients. The patients were divided into groups A or B, in accordance with the first allocated treatment. Subgroup analyses of the underlying diagnoses... (More)
Objective Short bowel syndrome patients frequently experience impaired health-related quality of life. This syndrome is also associated with increased costs for the individuals concerned and the community. Intake of specially processed cereals has been demonstrated to decrease intestinal secretion. This study evaluates the effect of a supplementary diet with specially processed cereals compared with nonprocessed cereals. Methods This investigation is a randomized double-blind, cross-over multicentre prospective study of 26 intestinal resected out patients, considered as short bowel syndrome patients. The patients were divided into groups A or B, in accordance with the first allocated treatment. Subgroup analyses of the underlying diagnoses and type of surgical procedure were performed. The studied parameters were faecal volume, nocturnal stools, abdominal pain/discomfort, health-related quality of life, peripheral blood tests and anthropometric data. Results In both groups, intake of norprocessed cereals significantly decreased the faecal volume. The subgroup analyses of patients with a history of ulcerative colitis (compared with Crohn's disease) and nonileostomy-operated procedure (compared with ileostomi-operated procedure) showed significantly decreased faecal volume during nonprocessed cereals intake. Peripheral blood tests, quality of life and anthropometry were not affected. Conclusion In this study, norprocessed cereals seemed to be as effective as specially processed cereals in decreasing faecal volume in general and especially in ulcerative colitis patients (mainly operated with nonileostomy techniques). Our results indicate that use of supplementary cereals is safe for this group of patients, but should optimally include evaluation of the underlying diagnosis and the surgical method used. Eur J Gastroenterol Hepatol 20:1085-1093 (C) 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins. (Less)
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publication status
published
subject
keywords
quality of life, malabsorption, cereals, diet therapy, short bowel, syndrome
in
European Journal of Gastroenterology and Hepathology
volume
20
issue
11
pages
1085 - 1093
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000260721000006
  • scopus:55349144898
ISSN
1473-5687
DOI
10.1097/MEG.0b013e328303c00a
language
English
LU publication?
yes
id
d0781a6c-cb77-4f74-aa4a-a188c36c07d8 (old id 1283935)
date added to LUP
2009-02-09 11:01:51
date last changed
2017-07-02 03:33:30
@article{d0781a6c-cb77-4f74-aa4a-a188c36c07d8,
  abstract     = {Objective Short bowel syndrome patients frequently experience impaired health-related quality of life. This syndrome is also associated with increased costs for the individuals concerned and the community. Intake of specially processed cereals has been demonstrated to decrease intestinal secretion. This study evaluates the effect of a supplementary diet with specially processed cereals compared with nonprocessed cereals. Methods This investigation is a randomized double-blind, cross-over multicentre prospective study of 26 intestinal resected out patients, considered as short bowel syndrome patients. The patients were divided into groups A or B, in accordance with the first allocated treatment. Subgroup analyses of the underlying diagnoses and type of surgical procedure were performed. The studied parameters were faecal volume, nocturnal stools, abdominal pain/discomfort, health-related quality of life, peripheral blood tests and anthropometric data. Results In both groups, intake of norprocessed cereals significantly decreased the faecal volume. The subgroup analyses of patients with a history of ulcerative colitis (compared with Crohn's disease) and nonileostomy-operated procedure (compared with ileostomi-operated procedure) showed significantly decreased faecal volume during nonprocessed cereals intake. Peripheral blood tests, quality of life and anthropometry were not affected. Conclusion In this study, norprocessed cereals seemed to be as effective as specially processed cereals in decreasing faecal volume in general and especially in ulcerative colitis patients (mainly operated with nonileostomy techniques). Our results indicate that use of supplementary cereals is safe for this group of patients, but should optimally include evaluation of the underlying diagnosis and the surgical method used. Eur J Gastroenterol Hepatol 20:1085-1093 (C) 2008 Wolters Kluwer Health | Lippincott Williams & Wilkins.},
  author       = {Pagoldh, Maria and Eriksson, Anders and Heimtun, Erling and Kvifors, Eva and Sternby, Berit and Blomquist, Lars and Lapidus, Annika and Suhr, Ole and Lange, Stefan and Karlbom, Urban and Nordstrom, Daniel and Rettrup, Bjoern},
  issn         = {1473-5687},
  keyword      = {quality of life,malabsorption,cereals,diet therapy,short bowel,syndrome},
  language     = {eng},
  number       = {11},
  pages        = {1085--1093},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {European Journal of Gastroenterology and Hepathology},
  title        = {Effects of a supplementary diet with specially processed cereals in patients with short bowel syndrome},
  url          = {http://dx.doi.org/10.1097/MEG.0b013e328303c00a},
  volume       = {20},
  year         = {2008},
}