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COPD and co-morbidities, with special emphasis on cardiovascular conditions

Löfdahl, Claes-Göran LU (2008) Workshop on Respiratory Epidemiologic Research In CLINICAL RESPIRATORY JOURNAL 2. p.59-63
Abstract
The concept of COPD as a systemic disease has been widely accepted in the past several years. In parallel, it has been emphasised that COPD morbidity and mortality is strongly related to co-morbid conditions. This review summarises some recent studies showing that in patients with COPID, the prevalence of cardiac failure is manifested in 10%-46% of the patients, and that up to 40% of patients with cardiac failure show evidence of COPD, about half of them not earlier diagnosed. Recent data also show an increased risk for arteriosclerotic manifestations in COPD patients, and cardiac complications are common causes of death in COPD patients. Other manifestations of the metabolic syndrome, as diabetes, are also over-represented in patients. It... (More)
The concept of COPD as a systemic disease has been widely accepted in the past several years. In parallel, it has been emphasised that COPD morbidity and mortality is strongly related to co-morbid conditions. This review summarises some recent studies showing that in patients with COPID, the prevalence of cardiac failure is manifested in 10%-46% of the patients, and that up to 40% of patients with cardiac failure show evidence of COPD, about half of them not earlier diagnosed. Recent data also show an increased risk for arteriosclerotic manifestations in COPD patients, and cardiac complications are common causes of death in COPD patients. Other manifestations of the metabolic syndrome, as diabetes, are also over-represented in patients. It is also a well-established fact that a low FEV1 is a risk factor for cardiovascular diseases and events. Mechanistically, a systemic inflammation in COPD could be a link to cardiovascular events. COPD raises inflammatory parameters and local anti-inflammatory treatment seems to have a potential to decrease the systemic inflammation and also to decrease cardiovascular events. (Less)
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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
systemic inflammation, mortality, morbidity, chronic airway obstruction, cardiovascular diseases
in
CLINICAL RESPIRATORY JOURNAL
volume
2
pages
59 - 63
publisher
Wiley-Blackwell
conference name
Workshop on Respiratory Epidemiologic Research
external identifiers
  • wos:000259610500008
  • scopus:77953625127
ISSN
1752-699X
1752-6981
DOI
10.1111/j.1752-699X.2008.00085.x
language
English
LU publication?
yes
id
1dd55d4f-66ae-42dc-86e1-259435d2b6fe (old id 1286785)
date added to LUP
2009-02-10 14:33:08
date last changed
2017-06-25 03:35:29
@inproceedings{1dd55d4f-66ae-42dc-86e1-259435d2b6fe,
  abstract     = {The concept of COPD as a systemic disease has been widely accepted in the past several years. In parallel, it has been emphasised that COPD morbidity and mortality is strongly related to co-morbid conditions. This review summarises some recent studies showing that in patients with COPID, the prevalence of cardiac failure is manifested in 10%-46% of the patients, and that up to 40% of patients with cardiac failure show evidence of COPD, about half of them not earlier diagnosed. Recent data also show an increased risk for arteriosclerotic manifestations in COPD patients, and cardiac complications are common causes of death in COPD patients. Other manifestations of the metabolic syndrome, as diabetes, are also over-represented in patients. It is also a well-established fact that a low FEV1 is a risk factor for cardiovascular diseases and events. Mechanistically, a systemic inflammation in COPD could be a link to cardiovascular events. COPD raises inflammatory parameters and local anti-inflammatory treatment seems to have a potential to decrease the systemic inflammation and also to decrease cardiovascular events.},
  author       = {Löfdahl, Claes-Göran},
  booktitle    = {CLINICAL RESPIRATORY JOURNAL},
  issn         = {1752-699X},
  keyword      = {systemic inflammation,mortality,morbidity,chronic airway obstruction,cardiovascular diseases},
  language     = {eng},
  pages        = {59--63},
  publisher    = {Wiley-Blackwell},
  title        = {COPD and co-morbidities, with special emphasis on cardiovascular conditions},
  url          = {http://dx.doi.org/10.1111/j.1752-699X.2008.00085.x},
  volume       = {2},
  year         = {2008},
}