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Hypobaric pressure exposure effects on cochlear frequency selectivity in fluctuating, low-frequency hearing loss.

Brännström, K J and Grenner, Jan LU (2009) In Journal of Laryngology and Otology 123. p.710-717
Abstract
Aim:To study the effects of hypobaric pressure chamber exposure on the cochlear frequency selectivity of subjects with monaural, fluctuating, low-frequency hearing loss, such as occurs in Ménière's disease.Methods:We used a hypobaric pressure chamber to create relative underpressure in the ear canal, in order to impose positive pressure gradients on the inner ear. Psychophysical tuning curves, transiently evoked otoacoustic emissions and speech recognition scores in noise were measured in 10 subjects with fluctuating, low-frequency hearing loss, before and after pressure exposure.Results:After the exposure, subjects' overall pure tone averages showed no improvement, but individual results showed improved speech recognition scores in noise... (More)
Aim:To study the effects of hypobaric pressure chamber exposure on the cochlear frequency selectivity of subjects with monaural, fluctuating, low-frequency hearing loss, such as occurs in Ménière's disease.Methods:We used a hypobaric pressure chamber to create relative underpressure in the ear canal, in order to impose positive pressure gradients on the inner ear. Psychophysical tuning curves, transiently evoked otoacoustic emissions and speech recognition scores in noise were measured in 10 subjects with fluctuating, low-frequency hearing loss, before and after pressure exposure.Results:After the exposure, subjects' overall pure tone averages showed no improvement, but individual results showed improved speech recognition scores in noise (six subjects), increased transiently evoked otoacoustic emission strength (three subjects) and increased psychophysical tuning curve steepness (two subjects). Deteriorations were also seen, mainly in psychophysical tuning curves. No association could be established between the different tests, and the measured parameters could not predict subjective improvement.Conclusion:The results suggest variable effects of hypobaric pressure exposure on inner-ear physiology. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Laryngology and Otology
volume
123
pages
710 - 717
publisher
Cambridge University Press
external identifiers
  • wos:000267952500003
  • pmid:19134241
  • scopus:68149161088
ISSN
1748-5460
DOI
10.1017/S0022215109004228
language
English
LU publication?
yes
id
406f0235-2d81-4ec7-a345-04896e6cf8c2 (old id 1289825)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19134241?dopt=Abstract
date added to LUP
2009-02-03 11:00:23
date last changed
2017-01-01 07:30:35
@article{406f0235-2d81-4ec7-a345-04896e6cf8c2,
  abstract     = {Aim:To study the effects of hypobaric pressure chamber exposure on the cochlear frequency selectivity of subjects with monaural, fluctuating, low-frequency hearing loss, such as occurs in Ménière's disease.Methods:We used a hypobaric pressure chamber to create relative underpressure in the ear canal, in order to impose positive pressure gradients on the inner ear. Psychophysical tuning curves, transiently evoked otoacoustic emissions and speech recognition scores in noise were measured in 10 subjects with fluctuating, low-frequency hearing loss, before and after pressure exposure.Results:After the exposure, subjects' overall pure tone averages showed no improvement, but individual results showed improved speech recognition scores in noise (six subjects), increased transiently evoked otoacoustic emission strength (three subjects) and increased psychophysical tuning curve steepness (two subjects). Deteriorations were also seen, mainly in psychophysical tuning curves. No association could be established between the different tests, and the measured parameters could not predict subjective improvement.Conclusion:The results suggest variable effects of hypobaric pressure exposure on inner-ear physiology.},
  author       = {Brännström, K J and Grenner, Jan},
  issn         = {1748-5460},
  language     = {eng},
  pages        = {710--717},
  publisher    = {Cambridge University Press},
  series       = {Journal of Laryngology and Otology},
  title        = {Hypobaric pressure exposure effects on cochlear frequency selectivity in fluctuating, low-frequency hearing loss.},
  url          = {http://dx.doi.org/10.1017/S0022215109004228},
  volume       = {123},
  year         = {2009},
}