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An experimental study of the dose response of polymer gel dosimeters imaged with x-ray computed tomography

Trapp, J V ; Bäck, Sven LU ; Lepage, M ; Michael, G and Baldock, C (2001) In Physics in Medicine and Biology 46(11). p.2939-2951
Abstract
Changes in the linear attenuation coefficient of polymer gel dosimeters post-irradiation enable the imaging of dose distributions by x-ray computed tomography (CT). Various compositions of polymer gel dosimeters manufactured from acrylamide (AA), and N,N'-methylene-bis-acrylamide (BIS) comonomers and gelatin or agarose gelling agents were investigated. This work shows that increasing the comonomer concentration increases the CT-dose sensitivity of the polymer gel dosimeter. This can be further increased by replacing gelatin with agarose. Varying the gelatin concentration however does not significantly change the CT-dose sensitivity. Among the compositions studied, dose resolution (D(delta)95%) was found to be optimal for polymer gel... (More)
Changes in the linear attenuation coefficient of polymer gel dosimeters post-irradiation enable the imaging of dose distributions by x-ray computed tomography (CT). Various compositions of polymer gel dosimeters manufactured from acrylamide (AA), and N,N'-methylene-bis-acrylamide (BIS) comonomers and gelatin or agarose gelling agents were investigated. This work shows that increasing the comonomer concentration increases the CT-dose sensitivity of the polymer gel dosimeter. This can be further increased by replacing gelatin with agarose. Varying the gelatin concentration however does not significantly change the CT-dose sensitivity. Among the compositions studied, dose resolution (D(delta)95%) was found to be optimal for polymer gel dosimeters comprising 5% gelatin, 3% AA, 3% BIS and 89% water. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physics in Medicine and Biology
volume
46
issue
11
pages
2939 - 2951
publisher
IOP Publishing
external identifiers
  • wos:000172331400012
  • scopus:0034758028
ISSN
1361-6560
DOI
10.1088/0031-9155/46/11/312
language
English
LU publication?
yes
id
7d6eacd0-06d0-44fd-8316-f32380cff5ce (old id 1297213)
date added to LUP
2016-04-04 10:10:50
date last changed
2022-02-21 02:45:43
@article{7d6eacd0-06d0-44fd-8316-f32380cff5ce,
  abstract     = {{Changes in the linear attenuation coefficient of polymer gel dosimeters post-irradiation enable the imaging of dose distributions by x-ray computed tomography (CT). Various compositions of polymer gel dosimeters manufactured from acrylamide (AA), and N,N'-methylene-bis-acrylamide (BIS) comonomers and gelatin or agarose gelling agents were investigated. This work shows that increasing the comonomer concentration increases the CT-dose sensitivity of the polymer gel dosimeter. This can be further increased by replacing gelatin with agarose. Varying the gelatin concentration however does not significantly change the CT-dose sensitivity. Among the compositions studied, dose resolution (D(delta)95%) was found to be optimal for polymer gel dosimeters comprising 5% gelatin, 3% AA, 3% BIS and 89% water.}},
  author       = {{Trapp, J V and Bäck, Sven and Lepage, M and Michael, G and Baldock, C}},
  issn         = {{1361-6560}},
  language     = {{eng}},
  number       = {{11}},
  pages        = {{2939--2951}},
  publisher    = {{IOP Publishing}},
  series       = {{Physics in Medicine and Biology}},
  title        = {{An experimental study of the dose response of polymer gel dosimeters imaged with x-ray computed tomography}},
  url          = {{http://dx.doi.org/10.1088/0031-9155/46/11/312}},
  doi          = {{10.1088/0031-9155/46/11/312}},
  volume       = {{46}},
  year         = {{2001}},
}