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Investigation and analysis of ferrous sulfate polyvinyl alcohol (PVA) gel dosimeter

Hill, Brendan; Bäck, Sven LU ; Lepage, Martin; Simpson, John; Healy, Brendan and Baldock, Clive (2002) In Physics in Medicine and Biology 47(23). p.4233-4246
Abstract
Ferrous sulfate (Fe(SO4)2) PVA gels were investigated for a range of absorbed doses up to 20 Gy using both magnetic resonance imaging (MRI) and spectrophotometry to determine R1 and optical density (OD) dose responses and G values. It was found that R1- and OD-dose sensitivities increased with O2 saturation or by the introduction of a freeze-thaw cycle during preparation of the PVA gel. The storage temperature of the Fe(SO4)2 PVA gel at -18 degrees C increased R1-dose sensitivity above that of gels stored at 5 degrees C. The addition of sucrose to the formulation was found to result in the largest increase in both R1- and OD-dose sensitivities. Fe(SO4)2 PVA gel with and without the addition of xylenol orange was demonstrated to have a G... (More)
Ferrous sulfate (Fe(SO4)2) PVA gels were investigated for a range of absorbed doses up to 20 Gy using both magnetic resonance imaging (MRI) and spectrophotometry to determine R1 and optical density (OD) dose responses and G values. It was found that R1- and OD-dose sensitivities increased with O2 saturation or by the introduction of a freeze-thaw cycle during preparation of the PVA gel. The storage temperature of the Fe(SO4)2 PVA gel at -18 degrees C increased R1-dose sensitivity above that of gels stored at 5 degrees C. The addition of sucrose to the formulation was found to result in the largest increase in both R1- and OD-dose sensitivities. Fe(SO4)2 PVA gel with and without the addition of xylenol orange was demonstrated to have a G value of approximately 20 ions/100 eV and with sucrose approximately 24 ions/100 eV. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physics in Medicine and Biology
volume
47
issue
23
pages
4233 - 4246
publisher
IOP Publishing
external identifiers
  • wos:000180279500010
  • scopus:0346736700
ISSN
1361-6560
DOI
10.1088/0031-9155/47/23/309
language
English
LU publication?
yes
id
dc8da7fd-e989-458e-bb5d-2ba6c3761cc2 (old id 1297442)
date added to LUP
2009-07-14 12:34:56
date last changed
2017-07-23 03:34:41
@article{dc8da7fd-e989-458e-bb5d-2ba6c3761cc2,
  abstract     = {Ferrous sulfate (Fe(SO4)2) PVA gels were investigated for a range of absorbed doses up to 20 Gy using both magnetic resonance imaging (MRI) and spectrophotometry to determine R1 and optical density (OD) dose responses and G values. It was found that R1- and OD-dose sensitivities increased with O2 saturation or by the introduction of a freeze-thaw cycle during preparation of the PVA gel. The storage temperature of the Fe(SO4)2 PVA gel at -18 degrees C increased R1-dose sensitivity above that of gels stored at 5 degrees C. The addition of sucrose to the formulation was found to result in the largest increase in both R1- and OD-dose sensitivities. Fe(SO4)2 PVA gel with and without the addition of xylenol orange was demonstrated to have a G value of approximately 20 ions/100 eV and with sucrose approximately 24 ions/100 eV.},
  author       = {Hill, Brendan and Bäck, Sven and Lepage, Martin and Simpson, John and Healy, Brendan and Baldock, Clive},
  issn         = {1361-6560},
  language     = {eng},
  number       = {23},
  pages        = {4233--4246},
  publisher    = {IOP Publishing},
  series       = {Physics in Medicine and Biology},
  title        = {Investigation and analysis of ferrous sulfate polyvinyl alcohol (PVA) gel dosimeter},
  url          = {http://dx.doi.org/10.1088/0031-9155/47/23/309},
  volume       = {47},
  year         = {2002},
}