Incidence of bullous pemphigoid in Sweden 2005–2012 : a nationwide population-based cohort study of 3761 patients
(2017) In Archives of Dermatological Research 309(9). p.721-727- Abstract
Studies that report the incidence of bullous pemphigoid from validated nationwide population-based registries are rare. The aim of this study was to estimate the incidence of bullous pemphigoid in Sweden 2005–2012. A population-based open cohort study was designed including all patients diagnosed by a dermatologist with bullous pemphigoid (BP) in Sweden from 2005 to 2012 (n = 3761), identified from the National Patient Register (NPR). The diagnosis of bullous pemphigoid in the NPR was recently validated from medical records, histopathological and immunopathological data by our group in a previous study. The average annual incidence of bullous pemphigoid was 7.1/100,000 (95% CI 6.5–7.7). Female to male ratio was 1.2:1, mean age at... (More)
Studies that report the incidence of bullous pemphigoid from validated nationwide population-based registries are rare. The aim of this study was to estimate the incidence of bullous pemphigoid in Sweden 2005–2012. A population-based open cohort study was designed including all patients diagnosed by a dermatologist with bullous pemphigoid (BP) in Sweden from 2005 to 2012 (n = 3761), identified from the National Patient Register (NPR). The diagnosis of bullous pemphigoid in the NPR was recently validated from medical records, histopathological and immunopathological data by our group in a previous study. The average annual incidence of bullous pemphigoid was 7.1/100,000 (95% CI 6.5–7.7). Female to male ratio was 1.2:1, mean age at diagnosis was 78.9 years. The age-specific incidence rate increased markedly after 80 years of age with an incidence peak between 90 and 99 years of age, 81.9/100,000 (95% CI 75.0–89.2). This large nationwide cohort study presents an adjusted incidence of BP of 7.1/100,000 (95% CI 6.5–7.7) in Sweden. The incidence of bullous pemphigoid is higher than expected and bullous pemphigoid is a common disease in the elderly population.
(Less)
- author
- Thorslund, Kristofer ; Seifert, Oliver ; Nilzén, Karin and Grönhagen, Carina LU
- organization
- publishing date
- 2017-09-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Bullous pemphigoid, Incidence, Population-based cohort study
- in
- Archives of Dermatological Research
- volume
- 309
- issue
- 9
- pages
- 721 - 727
- publisher
- Springer
- external identifiers
-
- pmid:28875235
- wos:000413313300005
- pmid:28875235
- scopus:85029001125
- ISSN
- 0340-3696
- DOI
- 10.1007/s00403-017-1778-4
- language
- English
- LU publication?
- yes
- id
- 12c922a9-f653-45e7-afca-1a7a802860ba
- date added to LUP
- 2017-10-09 11:38:29
- date last changed
- 2025-02-18 01:17:56
@article{12c922a9-f653-45e7-afca-1a7a802860ba,
abstract = {{<p>Studies that report the incidence of bullous pemphigoid from validated nationwide population-based registries are rare. The aim of this study was to estimate the incidence of bullous pemphigoid in Sweden 2005–2012. A population-based open cohort study was designed including all patients diagnosed by a dermatologist with bullous pemphigoid (BP) in Sweden from 2005 to 2012 (n = 3761), identified from the National Patient Register (NPR). The diagnosis of bullous pemphigoid in the NPR was recently validated from medical records, histopathological and immunopathological data by our group in a previous study. The average annual incidence of bullous pemphigoid was 7.1/100,000 (95% CI 6.5–7.7). Female to male ratio was 1.2:1, mean age at diagnosis was 78.9 years. The age-specific incidence rate increased markedly after 80 years of age with an incidence peak between 90 and 99 years of age, 81.9/100,000 (95% CI 75.0–89.2). This large nationwide cohort study presents an adjusted incidence of BP of 7.1/100,000 (95% CI 6.5–7.7) in Sweden. The incidence of bullous pemphigoid is higher than expected and bullous pemphigoid is a common disease in the elderly population.</p>}},
author = {{Thorslund, Kristofer and Seifert, Oliver and Nilzén, Karin and Grönhagen, Carina}},
issn = {{0340-3696}},
keywords = {{Bullous pemphigoid; Incidence; Population-based cohort study}},
language = {{eng}},
month = {{09}},
number = {{9}},
pages = {{721--727}},
publisher = {{Springer}},
series = {{Archives of Dermatological Research}},
title = {{Incidence of bullous pemphigoid in Sweden 2005–2012 : a nationwide population-based cohort study of 3761 patients}},
url = {{http://dx.doi.org/10.1007/s00403-017-1778-4}},
doi = {{10.1007/s00403-017-1778-4}},
volume = {{309}},
year = {{2017}},
}