Antiproliferative effects of peracetylated naphthoxylosides.
(2009) In Bioorganic & Medicinal Chemistry Letters 19. p.1763-1766- Abstract
- The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1302540
- author
- Aili, Ulrika
LU
; Jacobsson, Mårten
LU
; Johnsson, Richard
LU
; Mani, Katrin
LU
and Ellervik, Ulf LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Bioorganic & Medicinal Chemistry Letters
- volume
- 19
- pages
- 1763 - 1766
- publisher
- Elsevier
- external identifiers
-
- wos:000263933800051
- pmid:19217282
- scopus:61349168579
- ISSN
- 0960-894X
- DOI
- 10.1016/j.bmcl.2009.01.065
- language
- English
- LU publication?
- yes
- id
- 6159d8ad-ed70-47c9-9abe-738c5a6aaed6 (old id 1302540)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19217282?dopt=Abstract
- date added to LUP
- 2016-04-04 09:16:45
- date last changed
- 2024-01-12 11:25:34
@article{6159d8ad-ed70-47c9-9abe-738c5a6aaed6, abstract = {{The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.}}, author = {{Aili, Ulrika and Jacobsson, Mårten and Johnsson, Richard and Mani, Katrin and Ellervik, Ulf}}, issn = {{0960-894X}}, language = {{eng}}, pages = {{1763--1766}}, publisher = {{Elsevier}}, series = {{Bioorganic & Medicinal Chemistry Letters}}, title = {{Antiproliferative effects of peracetylated naphthoxylosides.}}, url = {{http://dx.doi.org/10.1016/j.bmcl.2009.01.065}}, doi = {{10.1016/j.bmcl.2009.01.065}}, volume = {{19}}, year = {{2009}}, }