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Antiproliferative effects of peracetylated naphthoxylosides.

Aili, Ulrika LU ; Jacobsson, Mårten LU ; Johnsson, Richard LU ; Mani, Katrin LU orcid and Ellervik, Ulf LU orcid (2009) In Bioorganic & Medicinal Chemistry Letters 19. p.1763-1766
Abstract
The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Bioorganic & Medicinal Chemistry Letters
volume
19
pages
1763 - 1766
publisher
Elsevier
external identifiers
  • wos:000263933800051
  • pmid:19217282
  • scopus:61349168579
ISSN
0960-894X
DOI
10.1016/j.bmcl.2009.01.065
language
English
LU publication?
yes
id
6159d8ad-ed70-47c9-9abe-738c5a6aaed6 (old id 1302540)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19217282?dopt=Abstract
date added to LUP
2016-04-04 09:16:45
date last changed
2024-01-12 11:25:34
@article{6159d8ad-ed70-47c9-9abe-738c5a6aaed6,
  abstract     = {{The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.}},
  author       = {{Aili, Ulrika and Jacobsson, Mårten and Johnsson, Richard and Mani, Katrin and Ellervik, Ulf}},
  issn         = {{0960-894X}},
  language     = {{eng}},
  pages        = {{1763--1766}},
  publisher    = {{Elsevier}},
  series       = {{Bioorganic & Medicinal Chemistry Letters}},
  title        = {{Antiproliferative effects of peracetylated naphthoxylosides.}},
  url          = {{http://dx.doi.org/10.1016/j.bmcl.2009.01.065}},
  doi          = {{10.1016/j.bmcl.2009.01.065}},
  volume       = {{19}},
  year         = {{2009}},
}