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Antiproliferative effects of peracetylated naphthoxylosides.

Aili, Ulrika LU ; Jacobsson, Mårten LU ; Johnsson, Richard LU ; Mani, Katrin LU and Ellervik, Ulf LU (2009) In Bioorganic & Medicinal Chemistry Letters 19. p.1763-1766
Abstract
The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Bioorganic & Medicinal Chemistry Letters
volume
19
pages
1763 - 1766
publisher
Elsevier
external identifiers
  • wos:000263933800051
  • pmid:19217282
  • scopus:61349168579
ISSN
1090-2120
DOI
10.1016/j.bmcl.2009.01.065
language
English
LU publication?
yes
id
6159d8ad-ed70-47c9-9abe-738c5a6aaed6 (old id 1302540)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19217282?dopt=Abstract
date added to LUP
2009-03-09 10:54:21
date last changed
2017-04-09 04:33:22
@article{6159d8ad-ed70-47c9-9abe-738c5a6aaed6,
  abstract     = {The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.},
  author       = {Aili, Ulrika and Jacobsson, Mårten and Johnsson, Richard and Mani, Katrin and Ellervik, Ulf},
  issn         = {1090-2120},
  language     = {eng},
  pages        = {1763--1766},
  publisher    = {Elsevier},
  series       = {Bioorganic & Medicinal Chemistry Letters},
  title        = {Antiproliferative effects of peracetylated naphthoxylosides.},
  url          = {http://dx.doi.org/10.1016/j.bmcl.2009.01.065},
  volume       = {19},
  year         = {2009},
}