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Circulating particles during cardiac surgery.

Bjursten, Henrik LU ; Eyjolfsson, Atli LU ; Scicluna, Sara LU ; Paulsson, Per LU and Johnsson, Per (2009) In Interactive Cardiovascular and Thoracic Surgery
Abstract
Shed blood is known to be a source of lipid micro-emboli in cardiac surgery. The aim of this study was to characterize the occurrence of these particles at different stages of the operation, and to study their occurrence in the circulation at multiple time-points after the retransfusion of shed blood. 44 patients undergoing routine surgery with cardiopulmonary bypass were included. Blood was sampled from the surgical field at different sampling locations during the operation. Shed blood was collected in a transfusion bag and retransfused. After which, blood was sampled from the arterial line of the heart-lung machine. A Coulter counter was used for particle determinion. The mean volume of shed blood collected was 340+/-215 ml. Particles in... (More)
Shed blood is known to be a source of lipid micro-emboli in cardiac surgery. The aim of this study was to characterize the occurrence of these particles at different stages of the operation, and to study their occurrence in the circulation at multiple time-points after the retransfusion of shed blood. 44 patients undergoing routine surgery with cardiopulmonary bypass were included. Blood was sampled from the surgical field at different sampling locations during the operation. Shed blood was collected in a transfusion bag and retransfused. After which, blood was sampled from the arterial line of the heart-lung machine. A Coulter counter was used for particle determinion. The mean volume of shed blood collected was 340+/-215 ml. Particles in the size range 10-60 microm were found at varying concentrations, with the highest concentrations being found in blood collected after cannulation and from the pleura. After retransfusion of this blood, a biphasic response was seen in the blood drawn from the efferent line of the heart-lung machine. Particles are found in shed blood at all times during cardiac surgery, and when this blood was retransfused an increase was seen in particle concentration in the heart-lung machine. Keywords: Particles; Lipid particles; Circulation; Shed mediastinal blood. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Interactive Cardiovascular and Thoracic Surgery
publisher
European Association of Cardio-Thoracic Surgery
external identifiers
  • pmid:19208660
  • scopus:65949084234
ISSN
1569-9285
DOI
10.1510/icvts.2008.187021
language
English
LU publication?
yes
id
7bddfd7c-b53f-4247-9fa0-862d99f8ef6c (old id 1302696)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19208660?dopt=Abstract
date added to LUP
2009-03-05 08:36:59
date last changed
2017-11-19 04:18:34
@article{7bddfd7c-b53f-4247-9fa0-862d99f8ef6c,
  abstract     = {Shed blood is known to be a source of lipid micro-emboli in cardiac surgery. The aim of this study was to characterize the occurrence of these particles at different stages of the operation, and to study their occurrence in the circulation at multiple time-points after the retransfusion of shed blood. 44 patients undergoing routine surgery with cardiopulmonary bypass were included. Blood was sampled from the surgical field at different sampling locations during the operation. Shed blood was collected in a transfusion bag and retransfused. After which, blood was sampled from the arterial line of the heart-lung machine. A Coulter counter was used for particle determinion. The mean volume of shed blood collected was 340+/-215 ml. Particles in the size range 10-60 microm were found at varying concentrations, with the highest concentrations being found in blood collected after cannulation and from the pleura. After retransfusion of this blood, a biphasic response was seen in the blood drawn from the efferent line of the heart-lung machine. Particles are found in shed blood at all times during cardiac surgery, and when this blood was retransfused an increase was seen in particle concentration in the heart-lung machine. Keywords: Particles; Lipid particles; Circulation; Shed mediastinal blood.},
  author       = {Bjursten, Henrik and Eyjolfsson, Atli and Scicluna, Sara and Paulsson, Per and Johnsson, Per},
  issn         = {1569-9285},
  language     = {eng},
  month        = {02},
  publisher    = {European Association of Cardio-Thoracic Surgery},
  series       = {Interactive Cardiovascular and Thoracic Surgery},
  title        = {Circulating particles during cardiac surgery.},
  url          = {http://dx.doi.org/10.1510/icvts.2008.187021},
  year         = {2009},
}