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Postpartum thromboembolism: severe events might be preventable using a new risk score model.

Lindqvist, Pelle LU ; Torsson, Jelena LU ; Almqvist, Asa and Björgell, Ola LU (2008) In Vascular Health and Risk Management 4(5). p.1081-1087
Abstract
BACKGROUND: Pregnancy-related venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality. A new risk assessment model for VTE in relation to pregnancy has been introduced in Sweden. We wished to determine the proportion of preventable VTE cases if the model had been in use and make a brief cost-benefit analysis. METHODS: A hospital-based retrospective case-control study of all postpartum thromboembolic instances of deep venous thrombosis and pulmonary embolisms during a 16-year period. Large anamnestic risk factors at the time of delivery were assessed. We correlated the findings with the new Swedish guidelines for thromboprophylaxis. RESULTS: We found 37 cases of postpartum VTE during the study period. Nineteen of... (More)
BACKGROUND: Pregnancy-related venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality. A new risk assessment model for VTE in relation to pregnancy has been introduced in Sweden. We wished to determine the proportion of preventable VTE cases if the model had been in use and make a brief cost-benefit analysis. METHODS: A hospital-based retrospective case-control study of all postpartum thromboembolic instances of deep venous thrombosis and pulmonary embolisms during a 16-year period. Large anamnestic risk factors at the time of delivery were assessed. We correlated the findings with the new Swedish guidelines for thromboprophylaxis. RESULTS: We found 37 cases of postpartum VTE during the study period. Nineteen of all VTE cases (51%) and eight out of eleven of cases of pulmonary embolism (73%) had two or more large anamnestic risk factors, ie, they would have been subjected to thromboprophylaxis if the new guidelines had been used. The cost of each preventable VTE was lower than treating a VTE. CONCLUSION: Approximately one-half of postpartum VTE cases and 70% of pulmonary emboli cases have at least two large risk factors and might be preventable using the new algorithm. From the perspective of the health care system the new recommendations appears to be cost-effective. (Less)
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organization
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type
Contribution to journal
publication status
published
subject
keywords
Fibrinolytic Agents: economics, Puerperal Disorders: economics, Fibrinolytic Agents: therapeutic use, Puerperal Disorders: etiology, Puerperal Disorders: prevention & control, Pulmonary Embolism: etiology, Pulmonary Embolism: economics, Thromboembolism: etiology, Thromboembolism: economics, Pulmonary Embolism: prevention & control, Venous Thrombosis: etiology, Thromboembolism: prevention & control, Venous Thrombosis: economics, Venous Thrombosis: prevention & control
in
Vascular Health and Risk Management
volume
4
issue
5
pages
1081 - 1087
publisher
Dove Press
external identifiers
  • pmid:19183756
  • scopus:56849111156
ISSN
1178-2048
language
English
LU publication?
yes
id
0777dedc-6b1e-4b7a-952e-e8f197172967 (old id 1302999)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19183756?dopt=Abstract
date added to LUP
2009-03-02 15:06:45
date last changed
2017-08-06 04:46:40
@article{0777dedc-6b1e-4b7a-952e-e8f197172967,
  abstract     = {BACKGROUND: Pregnancy-related venous thromboembolism (VTE) is a major cause of maternal morbidity and mortality. A new risk assessment model for VTE in relation to pregnancy has been introduced in Sweden. We wished to determine the proportion of preventable VTE cases if the model had been in use and make a brief cost-benefit analysis. METHODS: A hospital-based retrospective case-control study of all postpartum thromboembolic instances of deep venous thrombosis and pulmonary embolisms during a 16-year period. Large anamnestic risk factors at the time of delivery were assessed. We correlated the findings with the new Swedish guidelines for thromboprophylaxis. RESULTS: We found 37 cases of postpartum VTE during the study period. Nineteen of all VTE cases (51%) and eight out of eleven of cases of pulmonary embolism (73%) had two or more large anamnestic risk factors, ie, they would have been subjected to thromboprophylaxis if the new guidelines had been used. The cost of each preventable VTE was lower than treating a VTE. CONCLUSION: Approximately one-half of postpartum VTE cases and 70% of pulmonary emboli cases have at least two large risk factors and might be preventable using the new algorithm. From the perspective of the health care system the new recommendations appears to be cost-effective.},
  author       = {Lindqvist, Pelle and Torsson, Jelena and Almqvist, Asa and Björgell, Ola},
  issn         = {1178-2048},
  keyword      = {Fibrinolytic Agents: economics,Puerperal Disorders: economics,Fibrinolytic Agents: therapeutic use,Puerperal Disorders: etiology,Puerperal Disorders: prevention & control,Pulmonary Embolism: etiology,Pulmonary Embolism: economics,Thromboembolism: etiology,Thromboembolism: economics,Pulmonary Embolism: prevention & control,Venous Thrombosis: etiology,Thromboembolism: prevention & control,Venous Thrombosis: economics,Venous Thrombosis: prevention & control},
  language     = {eng},
  number       = {5},
  pages        = {1081--1087},
  publisher    = {Dove Press},
  series       = {Vascular Health and Risk Management},
  title        = {Postpartum thromboembolism: severe events might be preventable using a new risk score model.},
  volume       = {4},
  year         = {2008},
}