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Increased sporulation rate of epidemic clostridium difficile type 027/NAP1

Åkerlund, Thomas ; Persson, Ingela ; Unemo, Magnus ; Noren, Torbjörn ; Svenungsson, Bo ; Wullt, Marlene LU and Burman, Lars G (2008) In Journal of Clinical Microbiology 46(4). p.1530-1533
Abstract
Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Clinical Microbiology
volume
46
issue
4
pages
1530 - 1533
publisher
American Society for Microbiology
external identifiers
  • wos:000254866400062
  • scopus:42449157632
  • pmid:18287318
  • pmid:18287318
ISSN
1098-660X
DOI
10.1128/JCM.01964-07
language
English
LU publication?
yes
id
13146aba-da50-4304-bbdf-eb05d5e1f8f9 (old id 1206367)
date added to LUP
2016-04-01 13:41:01
date last changed
2022-03-06 07:06:24
@article{13146aba-da50-4304-bbdf-eb05d5e1f8f9,
  abstract     = {{Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.}},
  author       = {{Åkerlund, Thomas and Persson, Ingela and Unemo, Magnus and Noren, Torbjörn and Svenungsson, Bo and Wullt, Marlene and Burman, Lars G}},
  issn         = {{1098-660X}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{1530--1533}},
  publisher    = {{American Society for Microbiology}},
  series       = {{Journal of Clinical Microbiology}},
  title        = {{Increased sporulation rate of epidemic clostridium difficile type 027/NAP1}},
  url          = {{http://dx.doi.org/10.1128/JCM.01964-07}},
  doi          = {{10.1128/JCM.01964-07}},
  volume       = {{46}},
  year         = {{2008}},
}