Wound edge microvascular blood flow: effects of negative pressure wound therapy using gauze or polyurethane foam.
(2009) In Annals of Plastic Surgery 63(6). p.676-681- Abstract
- The aim of this study was to examine the effects of negative pressure wound therapy (NPWT) on wound edge microvascular blood flow, comparing different wound fillers. Wounds were created on the backs of 7 pigs. NPWT was applied, using either foam or gauze, at -50,-75, -100, -125, -150, or -175 mm Hg. Microvascular blood flow was measured in muscle tissue, subcutaneous tissue, and in the wound bed, at 0.5, 1, and 2.5 cm from the wound edge, using laser Doppler velocimetry. Similar patterns of blood flow response were observed when using foam or gauze. At 2.5 cm from the wound edge there was an increase in microvascular blood flow, while blood flow was decreased closer (0.5 cm) to the wound edge. The blood flow effects were similar at the... (More)
- The aim of this study was to examine the effects of negative pressure wound therapy (NPWT) on wound edge microvascular blood flow, comparing different wound fillers. Wounds were created on the backs of 7 pigs. NPWT was applied, using either foam or gauze, at -50,-75, -100, -125, -150, or -175 mm Hg. Microvascular blood flow was measured in muscle tissue, subcutaneous tissue, and in the wound bed, at 0.5, 1, and 2.5 cm from the wound edge, using laser Doppler velocimetry. Similar patterns of blood flow response were observed when using foam or gauze. At 2.5 cm from the wound edge there was an increase in microvascular blood flow, while blood flow was decreased closer (0.5 cm) to the wound edge. The blood flow effects were similar at the different levels of negative pressure in muscle tissue, subcutaneous tissue, and in the wound bed. Altered microvascular blood flow to the wound edge may be one of the mechanisms by which NPWT facilitates healing. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1512270
- author
- Malmsjö, Malin LU ; Ingemansson, Richard LU ; Martin, Robin and Huddleston, Elizabeth
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Annals of Plastic Surgery
- volume
- 63
- issue
- 6
- pages
- 676 - 681
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000272316400022
- pmid:19887926
- scopus:74249088281
- ISSN
- 1536-3708
- DOI
- 10.1097/SAP.0b013e31819ae01b
- language
- English
- LU publication?
- yes
- id
- 131725c4-03c9-4ff4-b11f-32234831d7ad (old id 1512270)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19887926?dopt=Abstract
- date added to LUP
- 2016-04-01 12:05:38
- date last changed
- 2024-02-23 18:34:17
@article{131725c4-03c9-4ff4-b11f-32234831d7ad,
abstract = {{The aim of this study was to examine the effects of negative pressure wound therapy (NPWT) on wound edge microvascular blood flow, comparing different wound fillers. Wounds were created on the backs of 7 pigs. NPWT was applied, using either foam or gauze, at -50,-75, -100, -125, -150, or -175 mm Hg. Microvascular blood flow was measured in muscle tissue, subcutaneous tissue, and in the wound bed, at 0.5, 1, and 2.5 cm from the wound edge, using laser Doppler velocimetry. Similar patterns of blood flow response were observed when using foam or gauze. At 2.5 cm from the wound edge there was an increase in microvascular blood flow, while blood flow was decreased closer (0.5 cm) to the wound edge. The blood flow effects were similar at the different levels of negative pressure in muscle tissue, subcutaneous tissue, and in the wound bed. Altered microvascular blood flow to the wound edge may be one of the mechanisms by which NPWT facilitates healing.}},
author = {{Malmsjö, Malin and Ingemansson, Richard and Martin, Robin and Huddleston, Elizabeth}},
issn = {{1536-3708}},
language = {{eng}},
number = {{6}},
pages = {{676--681}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Annals of Plastic Surgery}},
title = {{Wound edge microvascular blood flow: effects of negative pressure wound therapy using gauze or polyurethane foam.}},
url = {{http://dx.doi.org/10.1097/SAP.0b013e31819ae01b}},
doi = {{10.1097/SAP.0b013e31819ae01b}},
volume = {{63}},
year = {{2009}},
}