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Why chloroplasts and mitochondria contain genomes

Allen, John LU (2003) In Comperative and Functional Genomics 4(1). p.31-36
Abstract
Chloroplasts and mitochondria originated as bacterial symbionts. The larger, host cells acquired genetic information from their prokaryotic guests by lateral gene transfer. The prokaryotically-derived genes of the eukaryotic cell nucleus now function to encode the great majority of chloroplast and mitochondrial proteins, as well as many proteins of the nucleus and cytosol. Genes are copied and moved between cellular compartments with relative ease, and there is no established obstacle to successful import of any protein precursor from the cytosol. Yet chloroplasts and mitochondria have not abdicated all genes and gene expression to the nucleus and to cytosolic translation. What, then, do chloroplast- and mitochondrially-encoded proteins... (More)
Chloroplasts and mitochondria originated as bacterial symbionts. The larger, host cells acquired genetic information from their prokaryotic guests by lateral gene transfer. The prokaryotically-derived genes of the eukaryotic cell nucleus now function to encode the great majority of chloroplast and mitochondrial proteins, as well as many proteins of the nucleus and cytosol. Genes are copied and moved between cellular compartments with relative ease, and there is no established obstacle to successful import of any protein precursor from the cytosol. Yet chloroplasts and mitochondria have not abdicated all genes and gene expression to the nucleus and to cytosolic translation. What, then, do chloroplast- and mitochondrially-encoded proteins have in common that confers a selective advantage on the cytoplasmic location of their genes? The proposal advanced here is that co-location of chloroplast and mitochondrial genes with their gene products is required for rapid and direct regulatory coupling. Redox control of gene expression is suggested as the common feature of those chloroplast and mitochondrial proteins that are encoded in situ. Recent evidence is consistent with this hypothesis, and its underlying assumptions and predictions are described. Copyright © 2003 John Wiley & Sons, Ltd. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
gene expression, respiration, cytoplasmic organelles, photosynthesis, CORR, electron transport, redox regulation, cell evolution
in
Comperative and Functional Genomics
volume
4
issue
1
pages
31 - 36
publisher
John Wiley & Sons
external identifiers
  • wos:000181392000006
  • scopus:0037295044
ISSN
7700-2016
DOI
10.1002/cfg.245
language
English
LU publication?
yes
id
fd52068f-7746-45f4-ab84-fe9bf81e8e8c (old id 132641)
date added to LUP
2007-07-04 09:50:02
date last changed
2018-01-07 09:16:34
@article{fd52068f-7746-45f4-ab84-fe9bf81e8e8c,
  abstract     = {Chloroplasts and mitochondria originated as bacterial symbionts. The larger, host cells acquired genetic information from their prokaryotic guests by lateral gene transfer. The prokaryotically-derived genes of the eukaryotic cell nucleus now function to encode the great majority of chloroplast and mitochondrial proteins, as well as many proteins of the nucleus and cytosol. Genes are copied and moved between cellular compartments with relative ease, and there is no established obstacle to successful import of any protein precursor from the cytosol. Yet chloroplasts and mitochondria have not abdicated all genes and gene expression to the nucleus and to cytosolic translation. What, then, do chloroplast- and mitochondrially-encoded proteins have in common that confers a selective advantage on the cytoplasmic location of their genes? The proposal advanced here is that co-location of chloroplast and mitochondrial genes with their gene products is required for rapid and direct regulatory coupling. Redox control of gene expression is suggested as the common feature of those chloroplast and mitochondrial proteins that are encoded in situ. Recent evidence is consistent with this hypothesis, and its underlying assumptions and predictions are described. Copyright © 2003 John Wiley & Sons, Ltd.},
  author       = {Allen, John},
  issn         = {7700-2016},
  keyword      = {gene expression,respiration,cytoplasmic organelles,photosynthesis,CORR,electron transport,redox regulation,cell evolution},
  language     = {eng},
  number       = {1},
  pages        = {31--36},
  publisher    = {John Wiley & Sons},
  series       = {Comperative and Functional Genomics},
  title        = {Why chloroplasts and mitochondria contain genomes},
  url          = {http://dx.doi.org/10.1002/cfg.245},
  volume       = {4},
  year         = {2003},
}