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Airborne chemistry coupled to Raman spectroscopy

Santesson, Sabina LU ; Johansson, Jonas; Taylor, Lynne S; Levander, Ia; Fox, Shannon; Sepaniak, Michael and Nilsson, Staffan LU (2003) In Analytical Chemistry 75(9). p.2177-2180
Abstract
In this paper, the use of airborne chemistry (acoustically levitated drops) in combination with Raman spectroscopy is explored. We report herein the first Raman studies of crystallization processes in levitated drops and the first demonstration of surface-enhanced Raman scattering (SERS) detection in this medium. Crystallization studies on the model compounds benzamide and indomethacin resulted in the formation of two crystal modifications for each compound, suggesting that this methodology may be useful for investigation of polymorphs. SERS detection resulted in a signal enhancement of 27 000 for benzoic acid and 11 000 for rhodamine 6-G. The preliminary results presented here clearly indicate that several important applications of the... (More)
In this paper, the use of airborne chemistry (acoustically levitated drops) in combination with Raman spectroscopy is explored. We report herein the first Raman studies of crystallization processes in levitated drops and the first demonstration of surface-enhanced Raman scattering (SERS) detection in this medium. Crystallization studies on the model compounds benzamide and indomethacin resulted in the formation of two crystal modifications for each compound, suggesting that this methodology may be useful for investigation of polymorphs. SERS detection resulted in a signal enhancement of 27 000 for benzoic acid and 11 000 for rhodamine 6-G. The preliminary results presented here clearly indicate that several important applications of the combination between Raman spectroscopy and acoustic drop levitation can be expected in the future. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Analytical Chemistry
volume
75
issue
9
pages
2177 - 2180
publisher
The American Chemical Society
external identifiers
  • wos:000182662800044
  • pmid:12720359
  • scopus:0037695192
ISSN
1520-6882
DOI
10.1021/ac026302w
language
English
LU publication?
yes
id
36a1839f-ebef-4fc0-9696-c47bc0924203 (old id 132746)
date added to LUP
2007-06-27 14:57:48
date last changed
2018-02-04 03:30:17
@article{36a1839f-ebef-4fc0-9696-c47bc0924203,
  abstract     = {In this paper, the use of airborne chemistry (acoustically levitated drops) in combination with Raman spectroscopy is explored. We report herein the first Raman studies of crystallization processes in levitated drops and the first demonstration of surface-enhanced Raman scattering (SERS) detection in this medium. Crystallization studies on the model compounds benzamide and indomethacin resulted in the formation of two crystal modifications for each compound, suggesting that this methodology may be useful for investigation of polymorphs. SERS detection resulted in a signal enhancement of 27 000 for benzoic acid and 11 000 for rhodamine 6-G. The preliminary results presented here clearly indicate that several important applications of the combination between Raman spectroscopy and acoustic drop levitation can be expected in the future.},
  author       = {Santesson, Sabina and Johansson, Jonas and Taylor, Lynne S and Levander, Ia and Fox, Shannon and Sepaniak, Michael and Nilsson, Staffan},
  issn         = {1520-6882},
  language     = {eng},
  number       = {9},
  pages        = {2177--2180},
  publisher    = {The American Chemical Society},
  series       = {Analytical Chemistry},
  title        = {Airborne chemistry coupled to Raman spectroscopy},
  url          = {http://dx.doi.org/10.1021/ac026302w},
  volume       = {75},
  year         = {2003},
}