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A correlation found between contact allergy to stent material and restenosis of the coronary arteries.

Svedman, Cecilia LU ; Ekqvist, Susanne LU ; Möller, Halvor LU ; Björk, Jonas LU ; Pripp, Carl-Magnus; Gruvberger, Birgitta LU ; Holmström, Eva; Gustavsson, Carl Gunnar LU and Bruze, Magnus LU (2009) In Contact Dermatitis 60(3). p.158-164
Abstract
BACKGROUND: Metallic implants, stents, are increasingly being used especially in patients with stenosis of the cardiac vessels. Ten to thirty per cent of the patients suffer from restenosis regardless of aetiology. We have shown increased frequency of contact allergy to stent metals in stented patients. OBJECTIVES: To we evaluate whether contact allergy to stent material is a risk factor for restenosis. METHODS: Patients with stainless steel stents, with or without gold plating, were epicutaneously tested and answered a questionnaire. The restenosis rate was evaluated. RESULTS: We found a correlation between contact allergy to gold, gold stent, and restenosis (OR 2.3, CI 1.0-5.1, P = 0.04). The risk for restenosis was threefold increased... (More)
BACKGROUND: Metallic implants, stents, are increasingly being used especially in patients with stenosis of the cardiac vessels. Ten to thirty per cent of the patients suffer from restenosis regardless of aetiology. We have shown increased frequency of contact allergy to stent metals in stented patients. OBJECTIVES: To we evaluate whether contact allergy to stent material is a risk factor for restenosis. METHODS: Patients with stainless steel stents, with or without gold plating, were epicutaneously tested and answered a questionnaire. The restenosis rate was evaluated. RESULTS: We found a correlation between contact allergy to gold, gold stent, and restenosis (OR 2.3, CI 1.0-5.1, P = 0.04). The risk for restenosis was threefold increased when the patient was gold allergic and stented with a gold-plated stent. An increased degree of chest pain in gold-allergic patients stented with gold-plated stent was found. CONCLUSIONS: We found a correlation between contact allergy to gold, gold-stent, and restenosis. It may be of importance to consider contact allergy when developing new materials for stenting. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Contact Dermatitis
volume
60
issue
3
pages
158 - 164
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • wos:000263679600007
  • pmid:19260914
  • scopus:61349139887
ISSN
0105-1873
DOI
10.1111/j.1600-0536.2008.01502.x
language
English
LU publication?
yes
id
3a8360df-c085-4171-8b95-f98419e1f4d7 (old id 1368007)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19260914?dopt=Abstract
http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0536.2008.01502.x/abstract
date added to LUP
2009-04-03 12:58:03
date last changed
2017-03-26 04:26:54
@article{3a8360df-c085-4171-8b95-f98419e1f4d7,
  abstract     = {BACKGROUND: Metallic implants, stents, are increasingly being used especially in patients with stenosis of the cardiac vessels. Ten to thirty per cent of the patients suffer from restenosis regardless of aetiology. We have shown increased frequency of contact allergy to stent metals in stented patients. OBJECTIVES: To we evaluate whether contact allergy to stent material is a risk factor for restenosis. METHODS: Patients with stainless steel stents, with or without gold plating, were epicutaneously tested and answered a questionnaire. The restenosis rate was evaluated. RESULTS: We found a correlation between contact allergy to gold, gold stent, and restenosis (OR 2.3, CI 1.0-5.1, P = 0.04). The risk for restenosis was threefold increased when the patient was gold allergic and stented with a gold-plated stent. An increased degree of chest pain in gold-allergic patients stented with gold-plated stent was found. CONCLUSIONS: We found a correlation between contact allergy to gold, gold-stent, and restenosis. It may be of importance to consider contact allergy when developing new materials for stenting.},
  author       = {Svedman, Cecilia and Ekqvist, Susanne and Möller, Halvor and Björk, Jonas and Pripp, Carl-Magnus and Gruvberger, Birgitta and Holmström, Eva and Gustavsson, Carl Gunnar and Bruze, Magnus},
  issn         = {0105-1873},
  language     = {eng},
  number       = {3},
  pages        = {158--164},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Contact Dermatitis},
  title        = {A correlation found between contact allergy to stent material and restenosis of the coronary arteries.},
  url          = {http://dx.doi.org/10.1111/j.1600-0536.2008.01502.x},
  volume       = {60},
  year         = {2009},
}