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MHC diversity in two Acrocephalus species: the outbred Great reed warbler and the inbred Seychelles warbler

Richardson, David LU and Westerdahl, Helena LU (2003) In Molecular Ecology 12(12). p.3523-3529
Abstract
The Great reed warbler (GRW) and the Seychelles warbler (SW) are congeners with markedly different demographic histories. The GRW is a normal outbred bird species while the SW population remains isolated and inbred after undergoing a severe population bottleneck. We examined variation at Major Histocompatibility Complex (MHC) class I exon 3 using restriction fragment length polymorphism, denaturing gradient gel electrophoresis and DNA sequencing. Although genetic variation was higher in the GRW, considerable variation has been maintained in the SW. The ten exon 3 sequences found in the SW were as diverged from each other as were a random sub-sample of the 67 sequences from the GRW. There was evidence for balancing selection in both... (More)
The Great reed warbler (GRW) and the Seychelles warbler (SW) are congeners with markedly different demographic histories. The GRW is a normal outbred bird species while the SW population remains isolated and inbred after undergoing a severe population bottleneck. We examined variation at Major Histocompatibility Complex (MHC) class I exon 3 using restriction fragment length polymorphism, denaturing gradient gel electrophoresis and DNA sequencing. Although genetic variation was higher in the GRW, considerable variation has been maintained in the SW. The ten exon 3 sequences found in the SW were as diverged from each other as were a random sub-sample of the 67 sequences from the GRW. There was evidence for balancing selection in both species, and the phylogenetic analysis showing that the exon 3 sequences did not separate according to species, was consistent with transspecies evolution of the MHC. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Molecular Ecology
volume
12
issue
12
pages
3523 - 3529
publisher
Wiley-Blackwell
external identifiers
  • wos:000186648400030
  • pmid:14629367
  • scopus:0344668676
ISSN
0962-1083
DOI
10.1046/j.1365-294X.2003.02005.x
language
English
LU publication?
yes
id
e4da2607-6d9f-431d-86c8-0f752a0d2e2f (old id 137149)
date added to LUP
2007-06-25 12:45:58
date last changed
2018-10-03 10:16:48
@article{e4da2607-6d9f-431d-86c8-0f752a0d2e2f,
  abstract     = {The Great reed warbler (GRW) and the Seychelles warbler (SW) are congeners with markedly different demographic histories. The GRW is a normal outbred bird species while the SW population remains isolated and inbred after undergoing a severe population bottleneck. We examined variation at Major Histocompatibility Complex (MHC) class I exon 3 using restriction fragment length polymorphism, denaturing gradient gel electrophoresis and DNA sequencing. Although genetic variation was higher in the GRW, considerable variation has been maintained in the SW. The ten exon 3 sequences found in the SW were as diverged from each other as were a random sub-sample of the 67 sequences from the GRW. There was evidence for balancing selection in both species, and the phylogenetic analysis showing that the exon 3 sequences did not separate according to species, was consistent with transspecies evolution of the MHC.},
  author       = {Richardson, David and Westerdahl, Helena},
  issn         = {0962-1083},
  language     = {eng},
  number       = {12},
  pages        = {3523--3529},
  publisher    = {Wiley-Blackwell},
  series       = {Molecular Ecology},
  title        = {MHC diversity in two Acrocephalus species: the outbred Great reed warbler and the inbred Seychelles warbler},
  url          = {http://dx.doi.org/10.1046/j.1365-294X.2003.02005.x},
  volume       = {12},
  year         = {2003},
}