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Contact allergy to gold in patients with gold-plated intracoronary stents.

Svedman, Cecilia LU ; Tillman, C; Gustavsson, C G; Möller, Halvor LU ; Frennby, Bo LU and Bruze, Magnus LU (2005) In Contact Dermatitis 52(4). p.192-196
Abstract
An increasingly common and effective method for the treatment of atherosclerotic disease in the coronary arteries is percutaneous transluminal coronary angioplasty (PTCA) and stenting. The stents are made of different metals. An increased rate of restenosis when using gold-plated stents has been shown. Contact allergy to gold is common in many countries. Recently, a study has shown an increased rate of contact allergy to nickel among patients with restenosis and a nickel-containing stent. The aims of our study were to investigate whether there was an increased rate of contact allergy to gold among patients with gold-plated stents and if this increased the risk of restenosis. 22 patients who had received a gold-plated stent were patch... (More)
An increasingly common and effective method for the treatment of atherosclerotic disease in the coronary arteries is percutaneous transluminal coronary angioplasty (PTCA) and stenting. The stents are made of different metals. An increased rate of restenosis when using gold-plated stents has been shown. Contact allergy to gold is common in many countries. Recently, a study has shown an increased rate of contact allergy to nickel among patients with restenosis and a nickel-containing stent. The aims of our study were to investigate whether there was an increased rate of contact allergy to gold among patients with gold-plated stents and if this increased the risk of restenosis. 22 patients who had received a gold-plated stent were patch tested. An age- and sex-matched population of 88 patients, previously patch tested because of a suspected contact dermatitis, served as controls. In the stent group, 10/22 (45.5%) had a contact allergy to gold, in the control group 18/88 (20.5%); the difference is statistically significant (P = 0.04). There was no significant difference regarding frequency of restenosis. Our study indicates that there is a risk of sensitizing the patient when implanting a gold-plated stent. Further studies are needed to confirm these results and to evaluate whether there is an increased risk of restenosis. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Contact Dermatitis
volume
52
issue
4
pages
192 - 196
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • wos:000228744700004
  • pmid:16426306
  • scopus:18744374894
ISSN
0105-1873
DOI
10.1111/j.0105-1873.2005.00522.x
language
English
LU publication?
yes
id
c8bdbcf4-a394-4cd4-83d3-9948343a4a77 (old id 138269)
date added to LUP
2007-07-30 10:40:46
date last changed
2017-07-09 03:38:15
@article{c8bdbcf4-a394-4cd4-83d3-9948343a4a77,
  abstract     = {An increasingly common and effective method for the treatment of atherosclerotic disease in the coronary arteries is percutaneous transluminal coronary angioplasty (PTCA) and stenting. The stents are made of different metals. An increased rate of restenosis when using gold-plated stents has been shown. Contact allergy to gold is common in many countries. Recently, a study has shown an increased rate of contact allergy to nickel among patients with restenosis and a nickel-containing stent. The aims of our study were to investigate whether there was an increased rate of contact allergy to gold among patients with gold-plated stents and if this increased the risk of restenosis. 22 patients who had received a gold-plated stent were patch tested. An age- and sex-matched population of 88 patients, previously patch tested because of a suspected contact dermatitis, served as controls. In the stent group, 10/22 (45.5%) had a contact allergy to gold, in the control group 18/88 (20.5%); the difference is statistically significant (P = 0.04). There was no significant difference regarding frequency of restenosis. Our study indicates that there is a risk of sensitizing the patient when implanting a gold-plated stent. Further studies are needed to confirm these results and to evaluate whether there is an increased risk of restenosis.},
  author       = {Svedman, Cecilia and Tillman, C and Gustavsson, C G and Möller, Halvor and Frennby, Bo and Bruze, Magnus},
  issn         = {0105-1873},
  language     = {eng},
  number       = {4},
  pages        = {192--196},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Contact Dermatitis},
  title        = {Contact allergy to gold in patients with gold-plated intracoronary stents.},
  url          = {http://dx.doi.org/10.1111/j.0105-1873.2005.00522.x},
  volume       = {52},
  year         = {2005},
}