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Proteomics principles and challenges

Marko-Varga, György LU (2004) In Pure and Applied Chemistry 76(4). p.829-837
Abstract
Proteomics studies rely on high-resolving separation techniques whereby the biological complexity can be unraveled. Both gel-based and liquid-phase separation principles are needed in order to mine deeper into the low abundant area of the proteins expressed in human cell samples. The expression levels that can be reached today with proteomics technology are still only reaching part of all proteins present in complex biological samples. The challenge to be met is not an easy task and will, in many aspects, be determined by the speed and success whereby the analytical field can make milestone progress. Examples will be given from our research group on proteomics studies, as well as principles and challenges within this research area.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pure and Applied Chemistry
volume
76
issue
4
pages
829 - 837
publisher
IUPAC
external identifiers
  • wos:000222017100011
  • scopus:2942685456
ISSN
0033-4545
language
English
LU publication?
yes
id
468c09ff-0300-4645-b8d9-8d47ec52f492 (old id 138505)
alternative location
http://www.iupac.org/publications/pac/2004/7604/7604x0829.html
http://www.iupac.org/publications/pac/2004/pdf/7604x0829.pdf
date added to LUP
2007-06-27 11:07:42
date last changed
2017-01-01 06:48:29
@article{468c09ff-0300-4645-b8d9-8d47ec52f492,
  abstract     = {Proteomics studies rely on high-resolving separation techniques whereby the biological complexity can be unraveled. Both gel-based and liquid-phase separation principles are needed in order to mine deeper into the low abundant area of the proteins expressed in human cell samples. The expression levels that can be reached today with proteomics technology are still only reaching part of all proteins present in complex biological samples. The challenge to be met is not an easy task and will, in many aspects, be determined by the speed and success whereby the analytical field can make milestone progress. Examples will be given from our research group on proteomics studies, as well as principles and challenges within this research area.},
  author       = {Marko-Varga, György},
  issn         = {0033-4545},
  language     = {eng},
  number       = {4},
  pages        = {829--837},
  publisher    = {IUPAC},
  series       = {Pure and Applied Chemistry},
  title        = {Proteomics principles and challenges},
  volume       = {76},
  year         = {2004},
}