Proteomics principles and challenges
(2004) In Pure and Applied Chemistry 76(4). p.829-837- Abstract
- Proteomics studies rely on high-resolving separation techniques whereby the biological complexity can be unraveled. Both gel-based and liquid-phase separation principles are needed in order to mine deeper into the low abundant area of the proteins expressed in human cell samples. The expression levels that can be reached today with proteomics technology are still only reaching part of all proteins present in complex biological samples. The challenge to be met is not an easy task and will, in many aspects, be determined by the speed and success whereby the analytical field can make milestone progress. Examples will be given from our research group on proteomics studies, as well as principles and challenges within this research area.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/138505
- author
- Marko-Varga, György LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Pure and Applied Chemistry
- volume
- 76
- issue
- 4
- pages
- 829 - 837
- publisher
- IUPAC
- external identifiers
-
- wos:000222017100011
- scopus:2942685456
- ISSN
- 0033-4545
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)
- id
- 468c09ff-0300-4645-b8d9-8d47ec52f492 (old id 138505)
- alternative location
- http://www.iupac.org/publications/pac/2004/7604/7604x0829.html
- http://www.iupac.org/publications/pac/2004/pdf/7604x0829.pdf
- date added to LUP
- 2016-04-01 15:50:59
- date last changed
- 2022-01-28 07:33:14
@article{468c09ff-0300-4645-b8d9-8d47ec52f492,
abstract = {{Proteomics studies rely on high-resolving separation techniques whereby the biological complexity can be unraveled. Both gel-based and liquid-phase separation principles are needed in order to mine deeper into the low abundant area of the proteins expressed in human cell samples. The expression levels that can be reached today with proteomics technology are still only reaching part of all proteins present in complex biological samples. The challenge to be met is not an easy task and will, in many aspects, be determined by the speed and success whereby the analytical field can make milestone progress. Examples will be given from our research group on proteomics studies, as well as principles and challenges within this research area.}},
author = {{Marko-Varga, György}},
issn = {{0033-4545}},
language = {{eng}},
number = {{4}},
pages = {{829--837}},
publisher = {{IUPAC}},
series = {{Pure and Applied Chemistry}},
title = {{Proteomics principles and challenges}},
url = {{http://www.iupac.org/publications/pac/2004/7604/7604x0829.html}},
volume = {{76}},
year = {{2004}},
}