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Serum Amyloid A Protein and C-Reactive Protein in Normal Pregnancy and Preeclampsia.

Kristensen, Karl LU ; Wide-Swensson, Dag LU ; Lindström, Veronica LU ; Schmidt, C; Grubb, Anders LU and Strevens, Helena LU (2009) In Gynecologic and Obstetric Investigation 67(4). p.275-280
Abstract
Aims: To study plasma levels of serum amyloid A protein and C-reactive protein in pregnant women with and without preeclampsia and non-pregnant women. Plasma levels of haptoglobin, orosomucoid and ceruloplasmin were also analyzed. Methods: The study included 295 women with uncomplicated pregnancies, 57 women diagnosed with preeclampsia, and 58 healthy non-pregnant women. Plasma concentrations of acute phase proteins were analyzed by particle-enhanced immunoassays. Non-parametric Kruskal-Wallis and Mann-Whitney U tests were used to test differences between the groups. Results: Plasma levels of C-reactive protein and ceruloplasmin were increased in pregnant women with and without preeclampsia compared to non-pregnant women. Plasma levels of... (More)
Aims: To study plasma levels of serum amyloid A protein and C-reactive protein in pregnant women with and without preeclampsia and non-pregnant women. Plasma levels of haptoglobin, orosomucoid and ceruloplasmin were also analyzed. Methods: The study included 295 women with uncomplicated pregnancies, 57 women diagnosed with preeclampsia, and 58 healthy non-pregnant women. Plasma concentrations of acute phase proteins were analyzed by particle-enhanced immunoassays. Non-parametric Kruskal-Wallis and Mann-Whitney U tests were used to test differences between the groups. Results: Plasma levels of C-reactive protein and ceruloplasmin were increased in pregnant women with and without preeclampsia compared to non-pregnant women. Plasma levels of serum amyloid A protein and C-reactive protein were not elevated in women with preeclampsia compared to women with normal pregnancy. Conclusion: The description of preeclampsia as a systemic inflammatory state was not reflected in the plasma levels of serum amyloid A protein and C-reactive protein. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Gynecologic and Obstetric Investigation
volume
67
issue
4
pages
275 - 280
publisher
Karger
external identifiers
  • wos:000265865200009
  • pmid:19390201
  • scopus:65449145191
ISSN
1423-002X
DOI
10.1159/000214081
language
English
LU publication?
yes
id
f0865c42-6918-4327-982f-924294a7e452 (old id 1391884)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19390201?dopt=Abstract
date added to LUP
2009-05-05 14:43:53
date last changed
2017-01-01 07:33:09
@article{f0865c42-6918-4327-982f-924294a7e452,
  abstract     = {Aims: To study plasma levels of serum amyloid A protein and C-reactive protein in pregnant women with and without preeclampsia and non-pregnant women. Plasma levels of haptoglobin, orosomucoid and ceruloplasmin were also analyzed. Methods: The study included 295 women with uncomplicated pregnancies, 57 women diagnosed with preeclampsia, and 58 healthy non-pregnant women. Plasma concentrations of acute phase proteins were analyzed by particle-enhanced immunoassays. Non-parametric Kruskal-Wallis and Mann-Whitney U tests were used to test differences between the groups. Results: Plasma levels of C-reactive protein and ceruloplasmin were increased in pregnant women with and without preeclampsia compared to non-pregnant women. Plasma levels of serum amyloid A protein and C-reactive protein were not elevated in women with preeclampsia compared to women with normal pregnancy. Conclusion: The description of preeclampsia as a systemic inflammatory state was not reflected in the plasma levels of serum amyloid A protein and C-reactive protein.},
  author       = {Kristensen, Karl and Wide-Swensson, Dag and Lindström, Veronica and Schmidt, C and Grubb, Anders and Strevens, Helena},
  issn         = {1423-002X},
  language     = {eng},
  number       = {4},
  pages        = {275--280},
  publisher    = {Karger},
  series       = {Gynecologic and Obstetric Investigation},
  title        = {Serum Amyloid A Protein and C-Reactive Protein in Normal Pregnancy and Preeclampsia.},
  url          = {http://dx.doi.org/10.1159/000214081},
  volume       = {67},
  year         = {2009},
}