The effects of platelet transfusions evaluated using rotational thromboelastometry.
(2009) In Anesthesia and Analgesia 108(5). p.1430-1432- Abstract
- BACKGROUND: In this study, we assessed the immediate effects of platelet transfusion on whole blood coagulation. METHODS: Ten thrombocytopenic patients given a single unit platelet transfusion of 200-300 x 10(9) platelets had their coagulation status assessed before and immediately after transfusion using rotational thromboelastometry. RESULTS: Transfusion increased the median platelet count from 31.5 to 43.5 x 10(9)/L. Clot formation time decreased by 32% (P = 0.005), whereas maximum clot strength increased by 47% (P = 0.005). CONCLUSION: Statistically significant improvements in rotational thromboelastometry-measured parameters were observed in association with a mean increase of 12 x 109/L in platelet count after platelet transfusion in... (More)
- BACKGROUND: In this study, we assessed the immediate effects of platelet transfusion on whole blood coagulation. METHODS: Ten thrombocytopenic patients given a single unit platelet transfusion of 200-300 x 10(9) platelets had their coagulation status assessed before and immediately after transfusion using rotational thromboelastometry. RESULTS: Transfusion increased the median platelet count from 31.5 to 43.5 x 10(9)/L. Clot formation time decreased by 32% (P = 0.005), whereas maximum clot strength increased by 47% (P = 0.005). CONCLUSION: Statistically significant improvements in rotational thromboelastometry-measured parameters were observed in association with a mean increase of 12 x 109/L in platelet count after platelet transfusion in these patients. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1392050
- author
- Flisberg, Per LU ; Rundgren, Malin LU and Engström, Martin LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Thrombocytopenia: blood, Thrombocytopenia: therapy
- in
- Anesthesia and Analgesia
- volume
- 108
- issue
- 5
- pages
- 1430 - 1432
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- wos:000265422300012
- pmid:19372316
- scopus:65349092837
- pmid:19372316
- ISSN
- 1526-7598
- DOI
- 10.1213/ane.0b013e31819bccb7
- project
- Koagulation vid kirurgi och kritisk sjukdom
- language
- English
- LU publication?
- yes
- id
- d063f66b-67c4-4777-aae6-6a1a970bdedb (old id 1392050)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19372316?dopt=Abstract
- date added to LUP
- 2016-04-04 09:27:48
- date last changed
- 2022-03-31 02:55:35
@article{d063f66b-67c4-4777-aae6-6a1a970bdedb,
abstract = {{BACKGROUND: In this study, we assessed the immediate effects of platelet transfusion on whole blood coagulation. METHODS: Ten thrombocytopenic patients given a single unit platelet transfusion of 200-300 x 10(9) platelets had their coagulation status assessed before and immediately after transfusion using rotational thromboelastometry. RESULTS: Transfusion increased the median platelet count from 31.5 to 43.5 x 10(9)/L. Clot formation time decreased by 32% (P = 0.005), whereas maximum clot strength increased by 47% (P = 0.005). CONCLUSION: Statistically significant improvements in rotational thromboelastometry-measured parameters were observed in association with a mean increase of 12 x 109/L in platelet count after platelet transfusion in these patients.}},
author = {{Flisberg, Per and Rundgren, Malin and Engström, Martin}},
issn = {{1526-7598}},
keywords = {{Thrombocytopenia: blood; Thrombocytopenia: therapy}},
language = {{eng}},
number = {{5}},
pages = {{1430--1432}},
publisher = {{Lippincott Williams & Wilkins}},
series = {{Anesthesia and Analgesia}},
title = {{The effects of platelet transfusions evaluated using rotational thromboelastometry.}},
url = {{http://dx.doi.org/10.1213/ane.0b013e31819bccb7}},
doi = {{10.1213/ane.0b013e31819bccb7}},
volume = {{108}},
year = {{2009}},
}