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The effects of platelet transfusions evaluated using rotational thromboelastometry.

Flisberg, Per LU ; Rundgren, Malin LU and Engström, Martin LU (2009) In Anesthesia and Analgesia 108(5). p.1430-1432
Abstract
BACKGROUND: In this study, we assessed the immediate effects of platelet transfusion on whole blood coagulation. METHODS: Ten thrombocytopenic patients given a single unit platelet transfusion of 200-300 x 10(9) platelets had their coagulation status assessed before and immediately after transfusion using rotational thromboelastometry. RESULTS: Transfusion increased the median platelet count from 31.5 to 43.5 x 10(9)/L. Clot formation time decreased by 32% (P = 0.005), whereas maximum clot strength increased by 47% (P = 0.005). CONCLUSION: Statistically significant improvements in rotational thromboelastometry-measured parameters were observed in association with a mean increase of 12 x 109/L in platelet count after platelet transfusion in... (More)
BACKGROUND: In this study, we assessed the immediate effects of platelet transfusion on whole blood coagulation. METHODS: Ten thrombocytopenic patients given a single unit platelet transfusion of 200-300 x 10(9) platelets had their coagulation status assessed before and immediately after transfusion using rotational thromboelastometry. RESULTS: Transfusion increased the median platelet count from 31.5 to 43.5 x 10(9)/L. Clot formation time decreased by 32% (P = 0.005), whereas maximum clot strength increased by 47% (P = 0.005). CONCLUSION: Statistically significant improvements in rotational thromboelastometry-measured parameters were observed in association with a mean increase of 12 x 109/L in platelet count after platelet transfusion in these patients. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Thrombocytopenia: blood, Thrombocytopenia: therapy
in
Anesthesia and Analgesia
volume
108
issue
5
pages
1430 - 1432
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000265422300012
  • pmid:19372316
  • scopus:65349092837
ISSN
1526-7598
DOI
10.1213/ane.0b013e31819bccb7
language
English
LU publication?
yes
id
d063f66b-67c4-4777-aae6-6a1a970bdedb (old id 1392050)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19372316?dopt=Abstract
date added to LUP
2009-05-05 15:52:10
date last changed
2017-08-13 04:40:30
@article{d063f66b-67c4-4777-aae6-6a1a970bdedb,
  abstract     = {BACKGROUND: In this study, we assessed the immediate effects of platelet transfusion on whole blood coagulation. METHODS: Ten thrombocytopenic patients given a single unit platelet transfusion of 200-300 x 10(9) platelets had their coagulation status assessed before and immediately after transfusion using rotational thromboelastometry. RESULTS: Transfusion increased the median platelet count from 31.5 to 43.5 x 10(9)/L. Clot formation time decreased by 32% (P = 0.005), whereas maximum clot strength increased by 47% (P = 0.005). CONCLUSION: Statistically significant improvements in rotational thromboelastometry-measured parameters were observed in association with a mean increase of 12 x 109/L in platelet count after platelet transfusion in these patients.},
  author       = {Flisberg, Per and Rundgren, Malin and Engström, Martin},
  issn         = {1526-7598},
  keyword      = {Thrombocytopenia: blood,Thrombocytopenia: therapy},
  language     = {eng},
  number       = {5},
  pages        = {1430--1432},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {Anesthesia and Analgesia},
  title        = {The effects of platelet transfusions evaluated using rotational thromboelastometry.},
  url          = {http://dx.doi.org/10.1213/ane.0b013e31819bccb7},
  volume       = {108},
  year         = {2009},
}