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Biologically active metabolites from the basidiomycete Limacella illinita (Fr.) Murr.

Gruhn, Nina; Schoettler, Sylvia; Sterner, Olov LU and Anke, Timm (2007) In Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences 62(11-12). p.808-812
Abstract
In the course of our search for new bioactive compounds from basidiomycetes, four new compounds were isolated from fermentations of Limacella illinita. Illinitone A (1) exhibited weak phytotoxic and moderate nematicidal activities against Caenorhabditis elegans, illinitone B (2) was moderately cytotoxic, while limacellone (3) exhibited weak cytotoxic and phytotoxic activities. The muurolane sesquiterpene 4a was found to be inactive in the assays performed here. Limacellone (3), which appeared to be related with the illinitones 1 and 2, has a new C-15 carbon skeleton. It is possible that compounds 1, 2 and 3 are terpenoids/secoterpenoids, but their biosyntheses were not investigated.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
limacellone, Limacella illinita, illinitones, 11-desoxyeleganthol
in
Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences
volume
62
issue
11-12
pages
808 - 812
publisher
Verlag der Zeitschrift für Naturforschung
external identifiers
  • wos:000253174400006
  • scopus:38549114212
ISSN
0939-5075
language
English
LU publication?
yes
id
0c302c86-42fc-4c4d-aee9-b4b5327e568e (old id 1407496)
date added to LUP
2009-05-29 15:39:58
date last changed
2017-08-13 04:29:33
@article{0c302c86-42fc-4c4d-aee9-b4b5327e568e,
  abstract     = {In the course of our search for new bioactive compounds from basidiomycetes, four new compounds were isolated from fermentations of Limacella illinita. Illinitone A (1) exhibited weak phytotoxic and moderate nematicidal activities against Caenorhabditis elegans, illinitone B (2) was moderately cytotoxic, while limacellone (3) exhibited weak cytotoxic and phytotoxic activities. The muurolane sesquiterpene 4a was found to be inactive in the assays performed here. Limacellone (3), which appeared to be related with the illinitones 1 and 2, has a new C-15 carbon skeleton. It is possible that compounds 1, 2 and 3 are terpenoids/secoterpenoids, but their biosyntheses were not investigated.},
  author       = {Gruhn, Nina and Schoettler, Sylvia and Sterner, Olov and Anke, Timm},
  issn         = {0939-5075},
  keyword      = {limacellone,Limacella illinita,illinitones,11-desoxyeleganthol},
  language     = {eng},
  number       = {11-12},
  pages        = {808--812},
  publisher    = {Verlag der Zeitschrift für Naturforschung},
  series       = {Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences},
  title        = {Biologically active metabolites from the basidiomycete Limacella illinita (Fr.) Murr.},
  volume       = {62},
  year         = {2007},
}