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Non-intrusive optical study of gas and its exchange in human maxillary sinuses - art. no. 662804

Persson, Linda LU ; Andersson, Mats LU ; Svensson, Tomas LU ; Lewander, Märta LU ; Svanberg, Katarina LU and Svanberg, Sune LU (2007) Conference on Diagnostic Optical Spectroscopy in Biomedicine IV In Diagnostic Optical Spectroscopy in Biomedicine IV 6628. p.62804-62804
Abstract
We demonstrate a novel non-intrusive technique based on tunable diode laser absorption spectroscopy to investigate human maxillary sinuses in vivo. The technique relies on the fact that free gases have much sharper absorption features (typical a few GHz) than the surrounding tissue. Molecular oxygen was detected at 760 nm. Volunteers have been investigated by injecting near-infrared light fibre-optically in contact with the palate inside the mouth. The multiply scattered light was detected externally by a handheld probe on and around the cheek bone. A significant signal difference in oxygen imprint was observed when comparing volunteers with widely different anamnesis regarding maxillary sinus status. Control measurements through the hand... (More)
We demonstrate a novel non-intrusive technique based on tunable diode laser absorption spectroscopy to investigate human maxillary sinuses in vivo. The technique relies on the fact that free gases have much sharper absorption features (typical a few GHz) than the surrounding tissue. Molecular oxygen was detected at 760 nm. Volunteers have been investigated by injecting near-infrared light fibre-optically in contact with the palate inside the mouth. The multiply scattered light was detected externally by a handheld probe on and around the cheek bone. A significant signal difference in oxygen imprint was observed when comparing volunteers with widely different anamnesis regarding maxillary sinus status. Control measurements through the hand and through the cheek below the cheekbone were also performed to investigate any possible oxygen offset in the setup. These provided a consistently non-detectable signal level. The passages between the nasal cavity and the maxillary sinuses were also non-intrusively optically studied, to the best of our knowledge for the first time. These measurements provide information on the channel conductivity which may prove useful in facial sinus diagnostics. The results suggest that a clinical trial together with an ear-nose-throat (ENT) clinic should be carried out to investigate the clinical use of the new technique. (Less)
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author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
human sinuses, medicine, molecular oxygen, absorption, diode lasers, near infrared spectroscopy
in
Diagnostic Optical Spectroscopy in Biomedicine IV
volume
6628
pages
62804 - 62804
publisher
SPIE
conference name
Conference on Diagnostic Optical Spectroscopy in Biomedicine IV
external identifiers
  • wos:000251475200002
ISSN
0277-786X
1996-756X
DOI
10.1117/12.728120
language
English
LU publication?
yes
id
c3f5dcc7-0efe-4816-aa2a-3c10cd9def1f (old id 1409114)
date added to LUP
2009-06-01 16:16:25
date last changed
2017-11-20 15:06:00
@inproceedings{c3f5dcc7-0efe-4816-aa2a-3c10cd9def1f,
  abstract     = {We demonstrate a novel non-intrusive technique based on tunable diode laser absorption spectroscopy to investigate human maxillary sinuses in vivo. The technique relies on the fact that free gases have much sharper absorption features (typical a few GHz) than the surrounding tissue. Molecular oxygen was detected at 760 nm. Volunteers have been investigated by injecting near-infrared light fibre-optically in contact with the palate inside the mouth. The multiply scattered light was detected externally by a handheld probe on and around the cheek bone. A significant signal difference in oxygen imprint was observed when comparing volunteers with widely different anamnesis regarding maxillary sinus status. Control measurements through the hand and through the cheek below the cheekbone were also performed to investigate any possible oxygen offset in the setup. These provided a consistently non-detectable signal level. The passages between the nasal cavity and the maxillary sinuses were also non-intrusively optically studied, to the best of our knowledge for the first time. These measurements provide information on the channel conductivity which may prove useful in facial sinus diagnostics. The results suggest that a clinical trial together with an ear-nose-throat (ENT) clinic should be carried out to investigate the clinical use of the new technique.},
  author       = {Persson, Linda and Andersson, Mats and Svensson, Tomas and Lewander, Märta and Svanberg, Katarina and Svanberg, Sune},
  booktitle    = {Diagnostic Optical Spectroscopy in Biomedicine IV},
  issn         = {0277-786X},
  keyword      = {human sinuses,medicine,molecular oxygen,absorption,diode lasers,near infrared spectroscopy},
  language     = {eng},
  pages        = {62804--62804},
  publisher    = {SPIE},
  title        = {Non-intrusive optical study of gas and its exchange in human maxillary sinuses - art. no. 662804},
  url          = {http://dx.doi.org/10.1117/12.728120},
  volume       = {6628},
  year         = {2007},
}