Artificial carrier for oxygen supply in biological systems
(2004) In Applied Microbiology and Biotechnology 64(2). p.187-191- Abstract
- Several poly (dimethylsiloxanes) (PDMS) copolymers of dimethylsiloxane (DMS) with ethylene or propylene oxide were tested as artificial carriers for the delivery of oxygen to biological systems. Copolymers with a DMS content of 33% or lower enhanced glucose oxidation by 200% in contrast to the 25% increase produced by the same concentration of perfluorodecalin. When 0.05% of the copolymer with 18% DMS was included in the growth media of Bacillus thuriginensis, the biomass (growth rate) increased 1.5-fold. With 0.1% of this copolymer, actinorhodin production by Streptomyces coelicolor A3 (2) occurred in half the normal time and with an increased yield. In conclusion, these PDMS copolymers are a good alternative to perfluorodecalin as oxygen... (More)
- Several poly (dimethylsiloxanes) (PDMS) copolymers of dimethylsiloxane (DMS) with ethylene or propylene oxide were tested as artificial carriers for the delivery of oxygen to biological systems. Copolymers with a DMS content of 33% or lower enhanced glucose oxidation by 200% in contrast to the 25% increase produced by the same concentration of perfluorodecalin. When 0.05% of the copolymer with 18% DMS was included in the growth media of Bacillus thuriginensis, the biomass (growth rate) increased 1.5-fold. With 0.1% of this copolymer, actinorhodin production by Streptomyces coelicolor A3 (2) occurred in half the normal time and with an increased yield. In conclusion, these PDMS copolymers are a good alternative to perfluorodecalin as oxygen carriers in biotechnological processes. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/141051
- author
- Dey, Estera LU ; Norrlow, O and Liu, Yang LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied Microbiology and Biotechnology
- volume
- 64
- issue
- 2
- pages
- 187 - 191
- publisher
- Springer
- external identifiers
-
- wos:000220565100005
- pmid:14593505
- scopus:2142761526
- pmid:14593505
- ISSN
- 1432-0614
- DOI
- 10.1007/s00253-003-1454-9
- language
- English
- LU publication?
- yes
- id
- abc0576f-a9e4-4968-84fc-273d0bf2e265 (old id 141051)
- date added to LUP
- 2016-04-01 15:19:33
- date last changed
- 2022-01-28 04:48:41
@article{abc0576f-a9e4-4968-84fc-273d0bf2e265, abstract = {{Several poly (dimethylsiloxanes) (PDMS) copolymers of dimethylsiloxane (DMS) with ethylene or propylene oxide were tested as artificial carriers for the delivery of oxygen to biological systems. Copolymers with a DMS content of 33% or lower enhanced glucose oxidation by 200% in contrast to the 25% increase produced by the same concentration of perfluorodecalin. When 0.05% of the copolymer with 18% DMS was included in the growth media of Bacillus thuriginensis, the biomass (growth rate) increased 1.5-fold. With 0.1% of this copolymer, actinorhodin production by Streptomyces coelicolor A3 (2) occurred in half the normal time and with an increased yield. In conclusion, these PDMS copolymers are a good alternative to perfluorodecalin as oxygen carriers in biotechnological processes.}}, author = {{Dey, Estera and Norrlow, O and Liu, Yang}}, issn = {{1432-0614}}, language = {{eng}}, number = {{2}}, pages = {{187--191}}, publisher = {{Springer}}, series = {{Applied Microbiology and Biotechnology}}, title = {{Artificial carrier for oxygen supply in biological systems}}, url = {{http://dx.doi.org/10.1007/s00253-003-1454-9}}, doi = {{10.1007/s00253-003-1454-9}}, volume = {{64}}, year = {{2004}}, }