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Highly purified lipoteichoic acid from Staphylococcus aureus induces procoagulant activity and tissue factor expression in human monocytes but is a weak inducer in whole blood: Comparison with peptidoglycan

Mattsson, Eva LU ; Hartung, Thomas; Morath, Siegfried and Egesten, Arne LU (2004) In Infection and Immunity 72(7). p.4322-4326
Abstract
Lipoteichoic acid from Staphylococcus aureus was a potent inducer of procoagulant activity in isolated mononuclear cells but not in whole blood. In contrast, staphylococcal peptidoglycan showed equal levels of potency in isolated mononuclear cells and whole blood, suggesting that peptidoglycan is an important inducer of procoagulant activity in severe sepsis involving gram-positive bacteria.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Infection and Immunity
volume
72
issue
7
pages
4322 - 4326
publisher
American Society for Microbiology
external identifiers
  • wos:000222282800076
  • pmid:15213184
  • scopus:3042592600
ISSN
1098-5522
DOI
10.1128/IAI.72.7.4322-4326.2004
language
English
LU publication?
yes
id
98c22385-6843-4069-a122-202845d75a1a (old id 141855)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15213184&query_hl=53
date added to LUP
2007-07-26 09:39:58
date last changed
2017-01-01 05:12:59
@article{98c22385-6843-4069-a122-202845d75a1a,
  abstract     = {Lipoteichoic acid from Staphylococcus aureus was a potent inducer of procoagulant activity in isolated mononuclear cells but not in whole blood. In contrast, staphylococcal peptidoglycan showed equal levels of potency in isolated mononuclear cells and whole blood, suggesting that peptidoglycan is an important inducer of procoagulant activity in severe sepsis involving gram-positive bacteria.},
  author       = {Mattsson, Eva and Hartung, Thomas and Morath, Siegfried and Egesten, Arne},
  issn         = {1098-5522},
  language     = {eng},
  number       = {7},
  pages        = {4322--4326},
  publisher    = {American Society for Microbiology},
  series       = {Infection and Immunity},
  title        = {Highly purified lipoteichoic acid from Staphylococcus aureus induces procoagulant activity and tissue factor expression in human monocytes but is a weak inducer in whole blood: Comparison with peptidoglycan},
  url          = {http://dx.doi.org/10.1128/IAI.72.7.4322-4326.2004},
  volume       = {72},
  year         = {2004},
}