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Erythrocyte Mean Cell Volume—Correlation to Drinking Pattern in Heavy Alcoholics

TØNNESEN, HANNE LU ; HEJBERG, LISSIE ; FROBENIUS, STEEN and ANDERSEN, JENS RIKARDT (1986) In Acta Medica Scandinavica 219(5). p.515-518
Abstract

ABSTRACT. Erythrocyte mean cell volume (MCV) correlates well to alcohol intake in moderate alcoholism, but only about 50% of heavy drinkers have increased MCV. To evaluate the influence of the duration and extent of a drinking episode on MCV, 64 addictive alcoholics were investigated prospectively within two weeks after a drinking period. Their daily alcohol intake was 120–480 g and the actual drinking period has lasted for 1–104 weeks. For comparison, 21 non‐active alcoholics were investigated. There was no correlation between MCV of active alcoholics and daily alcohol consumption or smoking habits, whereas a significant positive correlation was found between MCV and both duration of actual drinking episode and total alcohol intake in... (More)

ABSTRACT. Erythrocyte mean cell volume (MCV) correlates well to alcohol intake in moderate alcoholism, but only about 50% of heavy drinkers have increased MCV. To evaluate the influence of the duration and extent of a drinking episode on MCV, 64 addictive alcoholics were investigated prospectively within two weeks after a drinking period. Their daily alcohol intake was 120–480 g and the actual drinking period has lasted for 1–104 weeks. For comparison, 21 non‐active alcoholics were investigated. There was no correlation between MCV of active alcoholics and daily alcohol consumption or smoking habits, whereas a significant positive correlation was found between MCV and both duration of actual drinking episode and total alcohol intake in this period. We conclude that MCV is probably of greater value in estimating the duration and extent of actual drinking episodes in heavy alcoholics than in screening for alcoholism. 1986 Association for the Publication of the Journal of Internal Medicine

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author
; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
alcoholism, drinking patterns, macrocytosis
in
Acta Medica Scandinavica
volume
219
issue
5
pages
515 - 518
publisher
Wiley-Blackwell
external identifiers
  • pmid:3739755
  • scopus:0022536170
ISSN
0001-6101
DOI
10.1111/j.0954-6820.1986.tb03348.x
language
English
LU publication?
no
id
14197d21-5312-4dfb-9e41-8ddb69cd4f78
date added to LUP
2022-10-31 18:32:52
date last changed
2025-01-11 02:30:06
@article{14197d21-5312-4dfb-9e41-8ddb69cd4f78,
  abstract     = {{<p>ABSTRACT.  Erythrocyte mean cell volume (MCV) correlates well to alcohol intake in moderate alcoholism, but only about 50% of heavy drinkers have increased MCV. To evaluate the influence of the duration and extent of a drinking episode on MCV, 64 addictive alcoholics were investigated prospectively within two weeks after a drinking period. Their daily alcohol intake was 120–480 g and the actual drinking period has lasted for 1–104 weeks. For comparison, 21 non‐active alcoholics were investigated. There was no correlation between MCV of active alcoholics and daily alcohol consumption or smoking habits, whereas a significant positive correlation was found between MCV and both duration of actual drinking episode and total alcohol intake in this period. We conclude that MCV is probably of greater value in estimating the duration and extent of actual drinking episodes in heavy alcoholics than in screening for alcoholism. 1986 Association for the Publication of the Journal of Internal Medicine</p>}},
  author       = {{TØNNESEN, HANNE and HEJBERG, LISSIE and FROBENIUS, STEEN and ANDERSEN, JENS RIKARDT}},
  issn         = {{0001-6101}},
  keywords     = {{alcoholism; drinking patterns; macrocytosis}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{515--518}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Medica Scandinavica}},
  title        = {{Erythrocyte Mean Cell Volume—Correlation to Drinking Pattern in Heavy Alcoholics}},
  url          = {{http://dx.doi.org/10.1111/j.0954-6820.1986.tb03348.x}},
  doi          = {{10.1111/j.0954-6820.1986.tb03348.x}},
  volume       = {{219}},
  year         = {{1986}},
}