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Impact of socioeconomic factors and antibiotic prescribing on penicillin- non-susceptible Streptococcus pneumoniae in the city of Malmö.

Nilsson Wimar, Percy LU and Laurell, Martin LU (2005) In Scandinavian Journal of Infectious Diseases 37(6). p.436-441
Abstract
Carriage or infection with penicillin-non-susceptible Streptococcus pneumoniae (PNSP) has been associated with antibiotic prescribing, socioeconomic factors, and attendance at day-care centres (DCCs). In the present study, linear regression was used to estimate the relation between these risk factors and the incidence of PNSP cases (non-susceptible defined as MIC >= 0.5 mu g/ml for penicillin) in 19 residential areas in Malmo. The number of PNSP cases was associated with the number of preschool children in the area (r=0.950, p<0.0001). The incidence of PNSP cases per 1000 children was positively correlated with antibiotic prescribing (r=0.614, p<0.01) but not with DCC attendance or any of the socioeconomic factors studied.... (More)
Carriage or infection with penicillin-non-susceptible Streptococcus pneumoniae (PNSP) has been associated with antibiotic prescribing, socioeconomic factors, and attendance at day-care centres (DCCs). In the present study, linear regression was used to estimate the relation between these risk factors and the incidence of PNSP cases (non-susceptible defined as MIC >= 0.5 mu g/ml for penicillin) in 19 residential areas in Malmo. The number of PNSP cases was associated with the number of preschool children in the area (r=0.950, p<0.0001). The incidence of PNSP cases per 1000 children was positively correlated with antibiotic prescribing (r=0.614, p<0.01) but not with DCC attendance or any of the socioeconomic factors studied. Antibiotic prescribing was, however, positively correlated with per capita income (r=0.597, p<0.05). Thus, even if higher socioeconomic status alone had no apparent influence on the incidence of PNSP in Malmo, there was still an indirect relation between these 2 factors, since inhabitants in these areas consumed more antibiotics. Based on these results, the spread of antibiotic-resistant pneumococci seems to be most reliably restricted by pursuing a restrictive policy regarding antibiotic prescription. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Scandinavian Journal of Infectious Diseases
volume
37
issue
6
pages
436 - 441
publisher
Informa Healthcare
external identifiers
  • wos:000230505200005
  • pmid:16012003
  • scopus:22844432336
ISSN
1651-1980
DOI
10.1080/00365540510037795
language
English
LU publication?
yes
id
3ac0be75-cb03-4da9-8616-db1a02d9c81f (old id 142179)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16012003&dopt=Abstract
date added to LUP
2007-07-26 11:39:15
date last changed
2017-01-01 07:14:37
@article{3ac0be75-cb03-4da9-8616-db1a02d9c81f,
  abstract     = {Carriage or infection with penicillin-non-susceptible Streptococcus pneumoniae (PNSP) has been associated with antibiotic prescribing, socioeconomic factors, and attendance at day-care centres (DCCs). In the present study, linear regression was used to estimate the relation between these risk factors and the incidence of PNSP cases (non-susceptible defined as MIC &gt;= 0.5 mu g/ml for penicillin) in 19 residential areas in Malmo. The number of PNSP cases was associated with the number of preschool children in the area (r=0.950, p&lt;0.0001). The incidence of PNSP cases per 1000 children was positively correlated with antibiotic prescribing (r=0.614, p&lt;0.01) but not with DCC attendance or any of the socioeconomic factors studied. Antibiotic prescribing was, however, positively correlated with per capita income (r=0.597, p&lt;0.05). Thus, even if higher socioeconomic status alone had no apparent influence on the incidence of PNSP in Malmo, there was still an indirect relation between these 2 factors, since inhabitants in these areas consumed more antibiotics. Based on these results, the spread of antibiotic-resistant pneumococci seems to be most reliably restricted by pursuing a restrictive policy regarding antibiotic prescription.},
  author       = {Nilsson Wimar, Percy and Laurell, Martin},
  issn         = {1651-1980},
  language     = {eng},
  number       = {6},
  pages        = {436--441},
  publisher    = {Informa Healthcare},
  series       = {Scandinavian Journal of Infectious Diseases},
  title        = {Impact of socioeconomic factors and antibiotic prescribing on penicillin- non-susceptible Streptococcus pneumoniae in the city of Malmö.},
  url          = {http://dx.doi.org/10.1080/00365540510037795},
  volume       = {37},
  year         = {2005},
}