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Carvone Contact Allergy in Southern Sweden : A 21-year Retrospective Study

Kroona, Liv; Isaksson, Marléne LU ; Ahlgren, Camilla; Dahlin, Jakob LU ; Bruze, Magnus LU and Warfvinge, Gunnar (2018) In Acta Dermato-Venereologica 98(10). p.938-942
Abstract

Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, were studied. Carvone-positive and carvone-negative patients were compared regarding patch test data from baseline series and dental series. Dental series-tested carvone-positive patients were also compared with a matched group. A total of 147 out of 4,221 referred patients had a positive patch test to carvone. Sensitized patients had higher mean... (More)

Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, were studied. Carvone-positive and carvone-negative patients were compared regarding patch test data from baseline series and dental series. Dental series-tested carvone-positive patients were also compared with a matched group. A total of 147 out of 4,221 referred patients had a positive patch test to carvone. Sensitized patients had higher mean age and were primarily women; 73% had oral signs and 57% had oral lichen. Concomitant patch test reactions to gold, nickel and mercury were common. In the matched group-comparison carvone-positive patients had a higher frequency of oral lichen, but no difference was found in sensitization to gold and mercury.

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organization
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published
subject
keywords
l-carvoneCAS:6485-40-1, patchtest:allergens:contactallergy:orallichenplanus:orallichenoidlesions, spearmint
in
Acta Dermato-Venereologica
volume
98
issue
10
pages
5 pages
publisher
Medical Journals Limited
external identifiers
  • scopus:85056285172
ISSN
1651-2057
DOI
10.2340/00015555-3009
language
English
LU publication?
yes
id
1422d141-e9ab-4c11-9453-6332873ec724
date added to LUP
2018-11-22 10:34:58
date last changed
2019-02-20 11:37:07
@article{1422d141-e9ab-4c11-9453-6332873ec724,
  abstract     = {<p>Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, were studied. Carvone-positive and carvone-negative patients were compared regarding patch test data from baseline series and dental series. Dental series-tested carvone-positive patients were also compared with a matched group. A total of 147 out of 4,221 referred patients had a positive patch test to carvone. Sensitized patients had higher mean age and were primarily women; 73% had oral signs and 57% had oral lichen. Concomitant patch test reactions to gold, nickel and mercury were common. In the matched group-comparison carvone-positive patients had a higher frequency of oral lichen, but no difference was found in sensitization to gold and mercury.</p>},
  author       = {Kroona, Liv and Isaksson, Marléne and Ahlgren, Camilla and Dahlin, Jakob and Bruze, Magnus and Warfvinge, Gunnar},
  issn         = {1651-2057},
  keyword      = {l-carvoneCAS:6485-40-1,patchtest:allergens:contactallergy:orallichenplanus:orallichenoidlesions,spearmint},
  language     = {eng},
  month        = {11},
  number       = {10},
  pages        = {938--942},
  publisher    = {Medical Journals Limited},
  series       = {Acta Dermato-Venereologica},
  title        = {Carvone Contact Allergy in Southern Sweden : A 21-year Retrospective Study},
  url          = {http://dx.doi.org/10.2340/00015555-3009},
  volume       = {98},
  year         = {2018},
}