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Closure of atrial septal defect in the adult. Cardiac remodeling is an early event.

Thilén, Ulf LU and Persson, S (2006) In International Journal of Cardiology 108(3). p.370-375
Abstract
Background: Study aimed to describe the extent and the temporal profile of cardiac remodeling after atrial septal defect closure in the adult. Methods: Prospective and longitudinal echocardiographic assessment of right and left heart size before and after (1 day-1 week/1/4/12 months) surgical or catheter-based atrial septal closure in 39 adults (age 54 15 years). Results: Right ventricular and atrial sizes were markedly reduced, left ventricular size increased and left atrial size remained unchanged after closure. Older age and a history of atrial fibrillation reduced the potential to normalize right and left atrial size after closure. The greater part of the changes occurred very early, in the 1st day/1st week, From then on the speed of... (More)
Background: Study aimed to describe the extent and the temporal profile of cardiac remodeling after atrial septal defect closure in the adult. Methods: Prospective and longitudinal echocardiographic assessment of right and left heart size before and after (1 day-1 week/1/4/12 months) surgical or catheter-based atrial septal closure in 39 adults (age 54 15 years). Results: Right ventricular and atrial sizes were markedly reduced, left ventricular size increased and left atrial size remained unchanged after closure. Older age and a history of atrial fibrillation reduced the potential to normalize right and left atrial size after closure. The greater part of the changes occurred very early, in the 1st day/1st week, From then on the speed of change gradually diminished and after 4 months no important changes were observed. The mode of closure did not influence the degree or the pace of the remodeling. Conclusion: Cardiac remodeling after atrial septal closure in the adult is a common and early event that seems by and large completed within the first half year after closure. The ventricles seem to have a higher capacity of remodeling than the atria in this setting. The mode of closure does not seem to significantly impact remodeling. (c) 2005 Elsevier Ireland Ltd. All rights reserved. (Less)
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author
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organization
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type
Contribution to journal
publication status
published
subject
keywords
atrial septal defect, congenital heart disease, remodeling, adult, closure
in
International Journal of Cardiology
volume
108
issue
3
pages
370 - 375
publisher
Elsevier
external identifiers
  • wos:000236475200012
  • scopus:33644783691
  • pmid:15982760
ISSN
0167-5273
DOI
10.1016/j.ijcard.2005.05.042
language
English
LU publication?
yes
id
6cd2b38f-fafe-4c96-96e3-d2552ef44588 (old id 142476)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15982760&dopt=Abstract
date added to LUP
2016-04-01 11:56:20
date last changed
2021-09-15 06:01:01
@article{6cd2b38f-fafe-4c96-96e3-d2552ef44588,
  abstract     = {Background: Study aimed to describe the extent and the temporal profile of cardiac remodeling after atrial septal defect closure in the adult. Methods: Prospective and longitudinal echocardiographic assessment of right and left heart size before and after (1 day-1 week/1/4/12 months) surgical or catheter-based atrial septal closure in 39 adults (age 54 15 years). Results: Right ventricular and atrial sizes were markedly reduced, left ventricular size increased and left atrial size remained unchanged after closure. Older age and a history of atrial fibrillation reduced the potential to normalize right and left atrial size after closure. The greater part of the changes occurred very early, in the 1st day/1st week, From then on the speed of change gradually diminished and after 4 months no important changes were observed. The mode of closure did not influence the degree or the pace of the remodeling. Conclusion: Cardiac remodeling after atrial septal closure in the adult is a common and early event that seems by and large completed within the first half year after closure. The ventricles seem to have a higher capacity of remodeling than the atria in this setting. The mode of closure does not seem to significantly impact remodeling. (c) 2005 Elsevier Ireland Ltd. All rights reserved.},
  author       = {Thilén, Ulf and Persson, S},
  issn         = {0167-5273},
  language     = {eng},
  number       = {3},
  pages        = {370--375},
  publisher    = {Elsevier},
  series       = {International Journal of Cardiology},
  title        = {Closure of atrial septal defect in the adult. Cardiac remodeling is an early event.},
  url          = {https://lup.lub.lu.se/search/files/2710838/624820.pdf},
  doi          = {10.1016/j.ijcard.2005.05.042},
  volume       = {108},
  year         = {2006},
}