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The impact of diabetes on coronary heart disease differs from that on ischaemic stroke with regard to the gender

Hyvarinen, Marjukka; Tuomilehto, Jaakko; Laatikainen, Tiina; Soderberg, Stefan; Eliasson, Mats; Nilsson, Peter LU and Qiao, Qing (2009) In Cardiovascular Diabetology 8.
Abstract
Background: To study the diabetes related CVD risk between men and women of different ages. Methods: Hazards ratios (HRs) (95%CI) for acute CHD and ischaemic stroke events were estimated based on data of Finnish and Swedish cohorts of 5111 women and 4167 men. Results: 182 (3.6%) women and 348 (8.4%) men had CHD and 129 (2.5%) women and 137 (3.3%) men ischaemic stroke events. The multivariate adjusted HRs for acute CHD at age groups of 40-49, 50-59 and 60-69 years were 1.00 (1.94), 1.78 (4.23), 3.75 (8.40) in women (men) without diabetes and 4.35 (5.40), 5.49 (9.54) and 8.84 (13.76) in women (men) with diabetes. The corresponding HRs for ischaemic stroke were 1.00 (1.26), 2.48 (2.83) and 5.17 (5.11) in women (men) without diabetes and 4.14... (More)
Background: To study the diabetes related CVD risk between men and women of different ages. Methods: Hazards ratios (HRs) (95%CI) for acute CHD and ischaemic stroke events were estimated based on data of Finnish and Swedish cohorts of 5111 women and 4167 men. Results: 182 (3.6%) women and 348 (8.4%) men had CHD and 129 (2.5%) women and 137 (3.3%) men ischaemic stroke events. The multivariate adjusted HRs for acute CHD at age groups of 40-49, 50-59 and 60-69 years were 1.00 (1.94), 1.78 (4.23), 3.75 (8.40) in women (men) without diabetes and 4.35 (5.40), 5.49 (9.54) and 8.84 (13.76) in women (men) with diabetes. The corresponding HRs for ischaemic stroke were 1.00 (1.26), 2.48 (2.83) and 5.17 (5.11) in women (men) without diabetes and 4.14 (4.91), 3.32 (6.75) and 13.91 (18.06) in women (men) with diabetes, respectively. Conclusion: CHD risk was higher in men than in women but difference reduced in diabetic population. Diabetes, however, increased stroke risk more in men than in women. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cardiovascular Diabetology
volume
8
publisher
BioMed Central
external identifiers
  • wos:000266003400001
  • scopus:65649132758
ISSN
1475-2840
DOI
10.1186/1475-2840-8-17
language
English
LU publication?
yes
id
87a29327-2467-4232-974f-287fd4105803 (old id 1426246)
date added to LUP
2009-06-30 11:36:19
date last changed
2017-11-12 03:41:52
@article{87a29327-2467-4232-974f-287fd4105803,
  abstract     = {Background: To study the diabetes related CVD risk between men and women of different ages. Methods: Hazards ratios (HRs) (95%CI) for acute CHD and ischaemic stroke events were estimated based on data of Finnish and Swedish cohorts of 5111 women and 4167 men. Results: 182 (3.6%) women and 348 (8.4%) men had CHD and 129 (2.5%) women and 137 (3.3%) men ischaemic stroke events. The multivariate adjusted HRs for acute CHD at age groups of 40-49, 50-59 and 60-69 years were 1.00 (1.94), 1.78 (4.23), 3.75 (8.40) in women (men) without diabetes and 4.35 (5.40), 5.49 (9.54) and 8.84 (13.76) in women (men) with diabetes. The corresponding HRs for ischaemic stroke were 1.00 (1.26), 2.48 (2.83) and 5.17 (5.11) in women (men) without diabetes and 4.14 (4.91), 3.32 (6.75) and 13.91 (18.06) in women (men) with diabetes, respectively. Conclusion: CHD risk was higher in men than in women but difference reduced in diabetic population. Diabetes, however, increased stroke risk more in men than in women.},
  author       = {Hyvarinen, Marjukka and Tuomilehto, Jaakko and Laatikainen, Tiina and Soderberg, Stefan and Eliasson, Mats and Nilsson, Peter and Qiao, Qing},
  issn         = {1475-2840},
  language     = {eng},
  publisher    = {BioMed Central},
  series       = {Cardiovascular Diabetology},
  title        = {The impact of diabetes on coronary heart disease differs from that on ischaemic stroke with regard to the gender},
  url          = {http://dx.doi.org/10.1186/1475-2840-8-17},
  volume       = {8},
  year         = {2009},
}