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Occurrence of Depression in Families with Frontotemporal Dementia: A Family History Study.

Horstmann, Vibeke LU and Gräsbeck, Anne LU (2009) In Neuroepidemiology 33(2). p.124-130
Abstract
Background: There are clinical similarities between frontotemporal dementia (FTD) and depression. The aim is to study co-aggregation of depression in families with FTD, indicating the existence of common aetiological factors. Methods: The study included 74 index patients with FTD and their 540 first-degree relatives above the age of 15 years. Occurrence of depression was studied at 3 different levels. Results: The incidence of depression in first-degree relatives of FTD patients was not higher than that of a general population. Occurrence of depression was not higher in families where parents had FTD compared to families with parents having no indications of FTD. Individuals with FTD had not suffered from depression to a greater extent... (More)
Background: There are clinical similarities between frontotemporal dementia (FTD) and depression. The aim is to study co-aggregation of depression in families with FTD, indicating the existence of common aetiological factors. Methods: The study included 74 index patients with FTD and their 540 first-degree relatives above the age of 15 years. Occurrence of depression was studied at 3 different levels. Results: The incidence of depression in first-degree relatives of FTD patients was not higher than that of a general population. Occurrence of depression was not higher in families where parents had FTD compared to families with parents having no indications of FTD. Individuals with FTD had not suffered from depression to a greater extent than those without FTD. Conclusions: The hypothesis of a common aetiological factor of FTD and depression was not supported. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Neuroepidemiology
volume
33
issue
2
pages
124 - 130
publisher
Karger
external identifiers
  • wos:000268897600007
  • pmid:19556807
  • scopus:67649195461
ISSN
1423-0208
DOI
10.1159/000226125
language
English
LU publication?
yes
id
6351a021-1e1f-4b3c-adc1-f6131ae075bd (old id 1433860)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19556807?dopt=Abstract
date added to LUP
2009-07-06 09:40:58
date last changed
2017-10-01 04:59:30
@article{6351a021-1e1f-4b3c-adc1-f6131ae075bd,
  abstract     = {Background: There are clinical similarities between frontotemporal dementia (FTD) and depression. The aim is to study co-aggregation of depression in families with FTD, indicating the existence of common aetiological factors. Methods: The study included 74 index patients with FTD and their 540 first-degree relatives above the age of 15 years. Occurrence of depression was studied at 3 different levels. Results: The incidence of depression in first-degree relatives of FTD patients was not higher than that of a general population. Occurrence of depression was not higher in families where parents had FTD compared to families with parents having no indications of FTD. Individuals with FTD had not suffered from depression to a greater extent than those without FTD. Conclusions: The hypothesis of a common aetiological factor of FTD and depression was not supported.},
  author       = {Horstmann, Vibeke and Gräsbeck, Anne},
  issn         = {1423-0208},
  language     = {eng},
  number       = {2},
  pages        = {124--130},
  publisher    = {Karger},
  series       = {Neuroepidemiology},
  title        = {Occurrence of Depression in Families with Frontotemporal Dementia: A Family History Study.},
  url          = {http://dx.doi.org/10.1159/000226125},
  volume       = {33},
  year         = {2009},
}