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Bone density 11 years after anorexia nervosa onset in a controlled study of 39 cases

Wentz, Elisabet; Mellström, Dan; Gillberg, Christopher; Sundh, Valter; Gillberg, Carina and Råstam, Maria LU (2003) In International Journal of Eating Disorders 34(3). p.8-314
Abstract
Objective

To evaluate bone mineral density (BMD) and body composition 11 years after the onset of anorexia nervosa (AN).



Method

Thirty-nine AN subjects (36 females, 3 males), selected from a population-based sample, and 46 matched controls (COMP; 43 females, 3 males) were examined by using double-energy X-ray absorptiometry (DXA). Only 2 women still had AN. None of the men had AN.



Results

The females in the AN and COMP groups did not differ regarding BMD, nor was there a difference across female groups concerning body mass index (BMI). The female AN group had a significantly lower percentage of body fat. BMD among females in the AN group was related to lowest BMI ever.... (More)
Objective

To evaluate bone mineral density (BMD) and body composition 11 years after the onset of anorexia nervosa (AN).



Method

Thirty-nine AN subjects (36 females, 3 males), selected from a population-based sample, and 46 matched controls (COMP; 43 females, 3 males) were examined by using double-energy X-ray absorptiometry (DXA). Only 2 women still had AN. None of the men had AN.



Results

The females in the AN and COMP groups did not differ regarding BMD, nor was there a difference across female groups concerning body mass index (BMI). The female AN group had a significantly lower percentage of body fat. BMD among females in the AN group was related to lowest BMI ever. There was an inverse relationship between lumbar BMD and AN duration.



Discussion

Low BMD is not overrepresented among weight-restored AN patients at long-term follow-up compared with healthy women. However, the inverse relationship between BMD and AN duration may be indicative of a risk for osteopenia in patients with subchronic and chronic AN. (Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adolescent Adult Anorexia Nervosa/complications* Body Composition* Body Weight Bone Density* Bone Diseases, Metabolic/etiology Case-Control Studies Female Follow-Up Studies Humans Male Risk Factors
in
International Journal of Eating Disorders
volume
34
issue
3
pages
8 - 314
publisher
John Wiley & Sons
external identifiers
  • scopus:0041384440
ISSN
1098-108X
DOI
10.1002/eat.10192
language
English
LU publication?
no
id
52872fd6-cba7-4bcc-b765-8959f9a26b5f (old id 1454688)
alternative location
http://onlinelibrary.wiley.com/doi/10.1002/eat.10192/abstract
date added to LUP
2011-02-21 20:18:01
date last changed
2018-01-07 06:20:23
@article{52872fd6-cba7-4bcc-b765-8959f9a26b5f,
  abstract     = {Objective <br/><br>
To evaluate bone mineral density (BMD) and body composition 11 years after the onset of anorexia nervosa (AN). <br/><br>
<br/><br>
Method <br/><br>
Thirty-nine AN subjects (36 females, 3 males), selected from a population-based sample, and 46 matched controls (COMP; 43 females, 3 males) were examined by using double-energy X-ray absorptiometry (DXA). Only 2 women still had AN. None of the men had AN. <br/><br>
<br/><br>
Results <br/><br>
The females in the AN and COMP groups did not differ regarding BMD, nor was there a difference across female groups concerning body mass index (BMI). The female AN group had a significantly lower percentage of body fat. BMD among females in the AN group was related to lowest BMI ever. There was an inverse relationship between lumbar BMD and AN duration. <br/><br>
<br/><br>
Discussion <br/><br>
Low BMD is not overrepresented among weight-restored AN patients at long-term follow-up compared with healthy women. However, the inverse relationship between BMD and AN duration may be indicative of a risk for osteopenia in patients with subchronic and chronic AN.},
  author       = {Wentz, Elisabet and Mellström, Dan and Gillberg, Christopher and Sundh, Valter and Gillberg, Carina and Råstam, Maria},
  issn         = {1098-108X},
  keyword      = {Adolescent
Adult
Anorexia Nervosa/complications*
Body Composition*
Body Weight
Bone Density*
Bone Diseases,Metabolic/etiology
Case-Control Studies
Female
Follow-Up Studies
Humans
Male
Risk Factors},
  language     = {eng},
  number       = {3},
  pages        = {8--314},
  publisher    = {John Wiley & Sons},
  series       = {International Journal of Eating Disorders},
  title        = {Bone density 11 years after anorexia nervosa onset in a controlled study of 39 cases},
  url          = {http://dx.doi.org/10.1002/eat.10192},
  volume       = {34},
  year         = {2003},
}