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A phylogenomic study of endosymbiotic bacteria

Canbäck, Björn LU ; Tamas, I and Andersson, S G E (2004) In Molecular Biology and Evolution 21(6). p.1110-1122
Abstract
Endosymbiotic bacteria of aphids, Buchnera aphidicola, and tsetse flies, Wigglesworthia glossinidia, are descendents of free-living gamma-Proteobacteria. The acceleration of sequence evolution in the endosymbiont genomes is here estimated from a phylogenomic analysis of the gamma-Proteobacteria. The tree topologies associated with the most highly conserved genes suggest that the endosymbionts form a sister group with Escherichia coli, Salmonella sp., and Yersinia pestis. Our results indicate that deviant tree topologies result from high substitution rates and biased nucleotide patterns, rather than from lateral gene transfer, as previously suggested. A reinvestigation of the relative rate increase in the endosymbiont genomes reveals... (More)
Endosymbiotic bacteria of aphids, Buchnera aphidicola, and tsetse flies, Wigglesworthia glossinidia, are descendents of free-living gamma-Proteobacteria. The acceleration of sequence evolution in the endosymbiont genomes is here estimated from a phylogenomic analysis of the gamma-Proteobacteria. The tree topologies associated with the most highly conserved genes suggest that the endosymbionts form a sister group with Escherichia coli, Salmonella sp., and Yersinia pestis. Our results indicate that deviant tree topologies result from high substitution rates and biased nucleotide patterns, rather than from lateral gene transfer, as previously suggested. A reinvestigation of the relative rate increase in the endosymbiont genomes reveals variability among genes that correlate with host-associated metabolic dependencies. The conclusion is that host-level selection has retarded both the loss of genes and the acceleration of sequence evolution in endocellular symbionts. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Molecular Biology and Evolution
volume
21
issue
6
pages
1110 - 1122
publisher
Oxford University Press
external identifiers
  • wos:000221599300016
  • pmid:15014155
  • scopus:2442667671
ISSN
0737-4038
DOI
10.1093/molbev/msh122
language
English
LU publication?
yes
id
1ff7c7d5-4601-454c-9809-85f0c6fd9bef (old id 146880)
date added to LUP
2007-06-29 09:24:39
date last changed
2017-10-22 03:35:19
@article{1ff7c7d5-4601-454c-9809-85f0c6fd9bef,
  abstract     = {Endosymbiotic bacteria of aphids, Buchnera aphidicola, and tsetse flies, Wigglesworthia glossinidia, are descendents of free-living gamma-Proteobacteria. The acceleration of sequence evolution in the endosymbiont genomes is here estimated from a phylogenomic analysis of the gamma-Proteobacteria. The tree topologies associated with the most highly conserved genes suggest that the endosymbionts form a sister group with Escherichia coli, Salmonella sp., and Yersinia pestis. Our results indicate that deviant tree topologies result from high substitution rates and biased nucleotide patterns, rather than from lateral gene transfer, as previously suggested. A reinvestigation of the relative rate increase in the endosymbiont genomes reveals variability among genes that correlate with host-associated metabolic dependencies. The conclusion is that host-level selection has retarded both the loss of genes and the acceleration of sequence evolution in endocellular symbionts.},
  author       = {Canbäck, Björn and Tamas, I and Andersson, S G E},
  issn         = {0737-4038},
  language     = {eng},
  number       = {6},
  pages        = {1110--1122},
  publisher    = {Oxford University Press},
  series       = {Molecular Biology and Evolution},
  title        = {A phylogenomic study of endosymbiotic bacteria},
  url          = {http://dx.doi.org/10.1093/molbev/msh122},
  volume       = {21},
  year         = {2004},
}