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Sclerosing Sweat Duct-Like Carcinoma of the Tongue-A Case Report and a Review of the Literature.

Petersson, Fredrik; Skogvall, Ingela LU and Elmberger, Göran (2009) In American Journal of Dermatopathology 31(7). p.691-694
Abstract
In this article, we present the second case of a tongue carcinoma with distinct morphological similarities to a primary sclerosing sweat duct carcinoma of the skin. The tumor infiltrated deeply into the striated muscle and exhibited extensive peri- and intraneural growth. Neoplastic cells had mildly pleomorphic nuclei and displayed in addition to small cysts, distinct duct formation with a bilayered epithelium. Mitotic figures were scarce. Despite extensive sampling, no precursor lesion-dysplasia-was found. The immunochemical study showed positive reaction for carcinoembryonic antigen, epithelial membrane antigen, cytokeratin (CK)7, low-molecular weight CK, BerEp4, high-molecular weight CK, CK5, and CK18. p63 was positive in the peripheral... (More)
In this article, we present the second case of a tongue carcinoma with distinct morphological similarities to a primary sclerosing sweat duct carcinoma of the skin. The tumor infiltrated deeply into the striated muscle and exhibited extensive peri- and intraneural growth. Neoplastic cells had mildly pleomorphic nuclei and displayed in addition to small cysts, distinct duct formation with a bilayered epithelium. Mitotic figures were scarce. Despite extensive sampling, no precursor lesion-dysplasia-was found. The immunochemical study showed positive reaction for carcinoembryonic antigen, epithelial membrane antigen, cytokeratin (CK)7, low-molecular weight CK, BerEp4, high-molecular weight CK, CK5, and CK18. p63 was positive in the peripheral parts of the neoplastic ducts with negative reaction in the luminal cells. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
American Journal of Dermatopathology
volume
31
issue
7
pages
691 - 694
publisher
Lippincott Williams & Wilkins
external identifiers
  • wos:000270537600013
  • pmid:19668074
  • scopus:70349748827
ISSN
1533-0311
DOI
10.1097/DAD.0b013e3181a5d246
language
English
LU publication?
yes
id
378801d2-16b3-41d5-9378-6e588770a693 (old id 1469869)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19668074?dopt=Abstract
date added to LUP
2012-01-18 13:56:43
date last changed
2017-01-01 04:22:16
@article{378801d2-16b3-41d5-9378-6e588770a693,
  abstract     = {In this article, we present the second case of a tongue carcinoma with distinct morphological similarities to a primary sclerosing sweat duct carcinoma of the skin. The tumor infiltrated deeply into the striated muscle and exhibited extensive peri- and intraneural growth. Neoplastic cells had mildly pleomorphic nuclei and displayed in addition to small cysts, distinct duct formation with a bilayered epithelium. Mitotic figures were scarce. Despite extensive sampling, no precursor lesion-dysplasia-was found. The immunochemical study showed positive reaction for carcinoembryonic antigen, epithelial membrane antigen, cytokeratin (CK)7, low-molecular weight CK, BerEp4, high-molecular weight CK, CK5, and CK18. p63 was positive in the peripheral parts of the neoplastic ducts with negative reaction in the luminal cells.},
  author       = {Petersson, Fredrik and Skogvall, Ingela and Elmberger, Göran},
  issn         = {1533-0311},
  language     = {eng},
  number       = {7},
  pages        = {691--694},
  publisher    = {Lippincott Williams & Wilkins},
  series       = {American Journal of Dermatopathology},
  title        = {Sclerosing Sweat Duct-Like Carcinoma of the Tongue-A Case Report and a Review of the Literature.},
  url          = {http://dx.doi.org/10.1097/DAD.0b013e3181a5d246},
  volume       = {31},
  year         = {2009},
}