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Reversibility of acute intermediate phase bilirubin encephalopathy

Hansen, Thor Willy Ruud ; Nietsch, Lutz ; Norman, Elisabeth LU ; Bjerre, Jesper Vandborg ; Hascoet, Jean-Michel ; Mreihil, Khalaf and Ebbesen, Finn (2009) In Acta Pædiatrica 98(10). p.1689-1694
Abstract
Aim: To show the potential for reversing acute intermediate to advanced phase bilirubin encephalopathy. Methods: Case studies. Results: Six extremely jaundiced infants had symptoms of intermediate to advanced phase acute bilirubin encephalopathy. The infants were treated aggressively. Two patients had brain magnetic resonance imaging showing increased signals in the globus pallidus. On follow-up, all infants are neurologically normal. Conclusions: Intermediate-to-advanced stage acute bilirubin encephalopathy may occasionally be reversible. These cases provide a strong argument in favour of rapid and aggressive intervention in infants presenting with extreme jaundice and neurological symptoms.
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Neonatal jaundice, globulin, Intravenous immune, Bilirubin encephalopathy, Exchange transfusion, Newborn, Phototherapy
in
Acta Pædiatrica
volume
98
issue
10
pages
1689 - 1694
publisher
Wiley-Blackwell
external identifiers
  • wos:000269491100032
  • scopus:69749102935
  • pmid:19583707
ISSN
1651-2227
DOI
10.1111/j.1651-2227.2009.01409.x
language
English
LU publication?
yes
id
e6069c10-f924-4444-9a56-36612975e4f0 (old id 1475319)
date added to LUP
2016-04-01 14:44:03
date last changed
2025-04-04 14:49:32
@article{e6069c10-f924-4444-9a56-36612975e4f0,
  abstract     = {{Aim: To show the potential for reversing acute intermediate to advanced phase bilirubin encephalopathy. Methods: Case studies. Results: Six extremely jaundiced infants had symptoms of intermediate to advanced phase acute bilirubin encephalopathy. The infants were treated aggressively. Two patients had brain magnetic resonance imaging showing increased signals in the globus pallidus. On follow-up, all infants are neurologically normal. Conclusions: Intermediate-to-advanced stage acute bilirubin encephalopathy may occasionally be reversible. These cases provide a strong argument in favour of rapid and aggressive intervention in infants presenting with extreme jaundice and neurological symptoms.}},
  author       = {{Hansen, Thor Willy Ruud and Nietsch, Lutz and Norman, Elisabeth and Bjerre, Jesper Vandborg and Hascoet, Jean-Michel and Mreihil, Khalaf and Ebbesen, Finn}},
  issn         = {{1651-2227}},
  keywords     = {{Neonatal jaundice; globulin; Intravenous immune; Bilirubin encephalopathy; Exchange transfusion; Newborn; Phototherapy}},
  language     = {{eng}},
  number       = {{10}},
  pages        = {{1689--1694}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Pædiatrica}},
  title        = {{Reversibility of acute intermediate phase bilirubin encephalopathy}},
  url          = {{http://dx.doi.org/10.1111/j.1651-2227.2009.01409.x}},
  doi          = {{10.1111/j.1651-2227.2009.01409.x}},
  volume       = {{98}},
  year         = {{2009}},
}