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Simulation of Nanoindentation Response of Empty and Filled Viral Capsids

Ahadi, Aylin LU (2009) Nordic Seminar in Computational Mechanics, NSCM-22 11.
Abstract
The nanoindentation response of empty and filled viral capsids is modelled using three dimensional finite element analysis. Simulation with two different geometries, spherical and icosahedral, are performed using the finite element code Abaqus. The capsids are modeled as non-linear Hookean elastic and both small and large deformation analysis is performed. Force-indentation curves for three different viral capsids are directly compared to experimental data and the Young’s modulus is determined by calibrating the force-indentation curve to data from atomic force microscopy (AFM) experiments. Predictions are made for two additional viral capsids. The results from the simulation showed a good agreement with AFM data, see [1].
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
FE simulation, nanoidentation, viral capsids
host publication
DCE Technical Memorandum
editor
Damkilde, Lars ; Andersen, Lars ; Schmidt Kristensen, Anders and Lund, Erik
volume
11
pages
4 pages
publisher
Aalborg University, Department of Civil Engineering
conference name
Nordic Seminar in Computational Mechanics, NSCM-22
conference location
Aalbord, Denmark
conference dates
2009-10-22 - 2009-10-23
ISSN
1901-7278
language
English
LU publication?
yes
id
21419325-f149-42f4-b464-ada75fa3e89b (old id 1483115)
date added to LUP
2016-04-01 14:13:55
date last changed
2018-11-21 20:24:44
@inproceedings{21419325-f149-42f4-b464-ada75fa3e89b,
  abstract     = {The nanoindentation response of empty and filled viral capsids is modelled using three dimensional finite element analysis. Simulation with two different geometries, spherical and icosahedral, are performed using the finite element code Abaqus. The capsids are modeled as non-linear Hookean elastic and both small and large deformation analysis is performed. Force-indentation curves for three different viral capsids are directly compared to experimental data and the Young’s modulus is determined by calibrating the force-indentation curve to data from atomic force microscopy (AFM) experiments. Predictions are made for two additional viral capsids. The results from the simulation showed a good agreement with AFM data, see [1].},
  author       = {Ahadi, Aylin},
  booktitle    = {DCE Technical Memorandum},
  editor       = {Damkilde, Lars and Andersen, Lars and Schmidt Kristensen, Anders and Lund, Erik},
  issn         = {1901-7278},
  language     = {eng},
  publisher    = {Aalborg University, Department of Civil Engineering},
  title        = {Simulation of Nanoindentation Response of Empty and Filled Viral Capsids},
  volume       = {11},
  year         = {2009},
}