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A large-scale screening of the normalized mammalian mitochondrial gene expression profiles.

Anisimov, Sergey LU (2005) In Genetical Research 86(2). p.127-138
Abstract
Mammalian mitochondrial genomes are organized in a conserved and extremely compact manner, encoding molecules that play a vital role in oxidative phosphorylation (OXPHOS) and carry out a number of other important biological functions. A large-scale screening of the normalized mitochondrial gene expression profiles generated from publicly available mammalian serial analysis of gene expression (SAGE) datasets (over 17·7 millions of tags) was performed in this study. Acquired SAGE libraries represent an extensive range of human, mouse, rat, bovine and swine cell and tissue samples (normal and pathological) in a variety of conditions. Using a straightforward in silico algorithm, variations in total mitochondrial gene expression, as well as in... (More)
Mammalian mitochondrial genomes are organized in a conserved and extremely compact manner, encoding molecules that play a vital role in oxidative phosphorylation (OXPHOS) and carry out a number of other important biological functions. A large-scale screening of the normalized mitochondrial gene expression profiles generated from publicly available mammalian serial analysis of gene expression (SAGE) datasets (over 17·7 millions of tags) was performed in this study. Acquired SAGE libraries represent an extensive range of human, mouse, rat, bovine and swine cell and tissue samples (normal and pathological) in a variety of conditions. Using a straightforward in silico algorithm, variations in total mitochondrial gene expression, as well as in the expression of individual genes encoded by mitochondrial genomes are addressed, and common patterns in the species- and tissue-specific mitochondrial gene expression profiles are discussed. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Genetical Research
volume
86
issue
2
pages
127 - 138
publisher
Cambridge University Press
external identifiers
  • pmid:16356286
  • wos:000234582400005
  • scopus:29244476056
ISSN
1469-5073
DOI
10.1017/S0016672305007718
language
English
LU publication?
yes
id
a41a52fa-e175-4695-8823-ea286b8d3bbf (old id 148678)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16356286&dopt=Abstract
date added to LUP
2007-07-09 16:34:16
date last changed
2017-01-01 06:47:19
@article{a41a52fa-e175-4695-8823-ea286b8d3bbf,
  abstract     = {Mammalian mitochondrial genomes are organized in a conserved and extremely compact manner, encoding molecules that play a vital role in oxidative phosphorylation (OXPHOS) and carry out a number of other important biological functions. A large-scale screening of the normalized mitochondrial gene expression profiles generated from publicly available mammalian serial analysis of gene expression (SAGE) datasets (over 17·7 millions of tags) was performed in this study. Acquired SAGE libraries represent an extensive range of human, mouse, rat, bovine and swine cell and tissue samples (normal and pathological) in a variety of conditions. Using a straightforward in silico algorithm, variations in total mitochondrial gene expression, as well as in the expression of individual genes encoded by mitochondrial genomes are addressed, and common patterns in the species- and tissue-specific mitochondrial gene expression profiles are discussed.},
  author       = {Anisimov, Sergey},
  issn         = {1469-5073},
  language     = {eng},
  number       = {2},
  pages        = {127--138},
  publisher    = {Cambridge University Press},
  series       = {Genetical Research},
  title        = {A large-scale screening of the normalized mammalian mitochondrial gene expression profiles.},
  url          = {http://dx.doi.org/10.1017/S0016672305007718},
  volume       = {86},
  year         = {2005},
}