A large-scale screening of the normalized mammalian mitochondrial gene expression profiles.
(2005) In Genetical Research 86(2). p.127-138- Abstract
- Mammalian mitochondrial genomes are organized in a conserved and extremely compact manner, encoding molecules that play a vital role in oxidative phosphorylation (OXPHOS) and carry out a number of other important biological functions. A large-scale screening of the normalized mitochondrial gene expression profiles generated from publicly available mammalian serial analysis of gene expression (SAGE) datasets (over 17·7 millions of tags) was performed in this study. Acquired SAGE libraries represent an extensive range of human, mouse, rat, bovine and swine cell and tissue samples (normal and pathological) in a variety of conditions. Using a straightforward in silico algorithm, variations in total mitochondrial gene expression, as well as in... (More)
- Mammalian mitochondrial genomes are organized in a conserved and extremely compact manner, encoding molecules that play a vital role in oxidative phosphorylation (OXPHOS) and carry out a number of other important biological functions. A large-scale screening of the normalized mitochondrial gene expression profiles generated from publicly available mammalian serial analysis of gene expression (SAGE) datasets (over 17·7 millions of tags) was performed in this study. Acquired SAGE libraries represent an extensive range of human, mouse, rat, bovine and swine cell and tissue samples (normal and pathological) in a variety of conditions. Using a straightforward in silico algorithm, variations in total mitochondrial gene expression, as well as in the expression of individual genes encoded by mitochondrial genomes are addressed, and common patterns in the species- and tissue-specific mitochondrial gene expression profiles are discussed. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/148678
- author
- Anisimov, Sergey LU
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Genetical Research
- volume
- 86
- issue
- 2
- pages
- 127 - 138
- publisher
- Cambridge University Press
- external identifiers
-
- pmid:16356286
- wos:000234582400005
- scopus:29244476056
- ISSN
- 1469-5073
- DOI
- 10.1017/S0016672305007718
- language
- English
- LU publication?
- yes
- id
- a41a52fa-e175-4695-8823-ea286b8d3bbf (old id 148678)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16356286&dopt=Abstract
- date added to LUP
- 2016-04-01 15:48:31
- date last changed
- 2022-04-22 17:33:07
@article{a41a52fa-e175-4695-8823-ea286b8d3bbf, abstract = {{Mammalian mitochondrial genomes are organized in a conserved and extremely compact manner, encoding molecules that play a vital role in oxidative phosphorylation (OXPHOS) and carry out a number of other important biological functions. A large-scale screening of the normalized mitochondrial gene expression profiles generated from publicly available mammalian serial analysis of gene expression (SAGE) datasets (over 17·7 millions of tags) was performed in this study. Acquired SAGE libraries represent an extensive range of human, mouse, rat, bovine and swine cell and tissue samples (normal and pathological) in a variety of conditions. Using a straightforward in silico algorithm, variations in total mitochondrial gene expression, as well as in the expression of individual genes encoded by mitochondrial genomes are addressed, and common patterns in the species- and tissue-specific mitochondrial gene expression profiles are discussed.}}, author = {{Anisimov, Sergey}}, issn = {{1469-5073}}, language = {{eng}}, number = {{2}}, pages = {{127--138}}, publisher = {{Cambridge University Press}}, series = {{Genetical Research}}, title = {{A large-scale screening of the normalized mammalian mitochondrial gene expression profiles.}}, url = {{https://lup.lub.lu.se/search/files/4478353/625187.pdf}}, doi = {{10.1017/S0016672305007718}}, volume = {{86}}, year = {{2005}}, }