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Correlation between carotid-femoral pulse wave velocity (PWV) at one measurement and 24-hour PWV in men and women assessed by two different methods in a population-based study

Nilsson, Peter LU and Johansson, Madeleine LU orcid (2024) European Society of Hypertension (ESH) Congress 2024 In Journal of Hypertension 42(Suppl 1). p.149-149
Abstract
Objective:
Aortic stiffness can be assessed by pulse wave velocity (PWV) using golden standard applanation tonometry (SphygmoCor; SC) or a 24-hour ambulatory oscillometric method (Arteriograph; AG). We aimed to compare AG with SC in a population-based study for PWV in men and women.

Design and method:
We used data from subjects (n= 1545; 748 men, 797 women; mean age 50 years, SD: 9.3) with complete data on both AG and SC from a population-based cohort. Correlations (Pearson's rho) were analyzed for PWV between carotid-femoral PWV using SC and aortic PWV (24-hours, daytime, nighttime) using AG stratified by sex. In addition, correlations with fasting plasma glucose (FPG) were analyzed after adjustment for... (More)
Objective:
Aortic stiffness can be assessed by pulse wave velocity (PWV) using golden standard applanation tonometry (SphygmoCor; SC) or a 24-hour ambulatory oscillometric method (Arteriograph; AG). We aimed to compare AG with SC in a population-based study for PWV in men and women.

Design and method:
We used data from subjects (n= 1545; 748 men, 797 women; mean age 50 years, SD: 9.3) with complete data on both AG and SC from a population-based cohort. Correlations (Pearson's rho) were analyzed for PWV between carotid-femoral PWV using SC and aortic PWV (24-hours, daytime, nighttime) using AG stratified by sex. In addition, correlations with fasting plasma glucose (FPG) were analyzed after adjustment for covariates.

Results:
Study characteristics are displayed in the Table. Mean PWV was higher in men and women when assessed by 24-hour AG (men: 9.1± 1.8 and women: 9.2± 1.5 m/s p=0.10) compared with SC (men: 7.9±1.5 and women: 8.3±1.6 m/s p<0.001). In women, SC-PWV was moderately correlated with 24-hour AG-PWV (r=0.43, p<0.001, Figure 1A), daytime AG-PWV (r=0.40, p<0.001), and nighttime AG-PWV (r=0.40, p<0.001). In men, SC-PWV was moderately correlated with 24-hour AG-PWV (r=0.41, p<0.001, Figure 1B) and nighttime AG-PWV (r=0.43, p<0.001), but less correlated with daytime AG-PWV (r=0.38, p<0.001). PWV also correlated with FPG levels.

Conclusions:
Mean PWV was lower when assessed by SphygmoCor compared with 24-hour Arteriograph in men and women. The methods were moderately correlated. Both measures of arterial stiffness were independently associated with fasting glycaemia in men, but significant only for SC-PWV in women, after full adjustment. Further studies are needed for prediction of cardiovascular endpoints comparing the methods. (Less)
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Aortic stiffness, vascular ageing, Population, Carotid-femoral pulse wave velocity
in
Journal of Hypertension
volume
42
issue
Suppl 1
pages
149 - 149
publisher
Lippincott Williams & Wilkins
conference name
European Society of Hypertension (ESH) Congress 2024
conference location
Berlin, Germany
conference dates
2024-05-31 - 2024-06-03
ISSN
1473-5598
DOI
10.1097/01.hjh.0001020852.04644.41
language
English
LU publication?
yes
id
14c3620e-17ac-4f7a-8e4b-c59346938ab6
date added to LUP
2024-06-26 22:58:19
date last changed
2025-04-04 14:36:43
@misc{14c3620e-17ac-4f7a-8e4b-c59346938ab6,
  abstract     = {{Objective: <br/>Aortic stiffness can be assessed by pulse wave velocity (PWV) using golden standard applanation tonometry (SphygmoCor; SC) or a 24-hour ambulatory oscillometric method (Arteriograph; AG). We aimed to compare AG with SC in a population-based study for PWV in men and women.<br/><br/>Design and method: <br/>We used data from subjects (n= 1545; 748 men, 797 women; mean age 50 years, SD: 9.3) with complete data on both AG and SC from a population-based cohort. Correlations (Pearson's rho) were analyzed for PWV between carotid-femoral PWV using SC and aortic PWV (24-hours, daytime, nighttime) using AG stratified by sex. In addition, correlations with fasting plasma glucose (FPG) were analyzed after adjustment for covariates.<br/><br/>Results: <br/>Study characteristics are displayed in the Table. Mean PWV was higher in men and women when assessed by 24-hour AG (men: 9.1± 1.8 and women: 9.2± 1.5 m/s p=0.10) compared with SC (men: 7.9±1.5 and women: 8.3±1.6 m/s p&lt;0.001). In women, SC-PWV was moderately correlated with 24-hour AG-PWV (r=0.43, p&lt;0.001, Figure 1A), daytime AG-PWV (r=0.40, p&lt;0.001), and nighttime AG-PWV (r=0.40, p&lt;0.001). In men, SC-PWV was moderately correlated with 24-hour AG-PWV (r=0.41, p&lt;0.001, Figure 1B) and nighttime AG-PWV (r=0.43, p&lt;0.001), but less correlated with daytime AG-PWV (r=0.38, p&lt;0.001). PWV also correlated with FPG levels.<br/><br/>Conclusions: <br/>Mean PWV was lower when assessed by SphygmoCor compared with 24-hour Arteriograph in men and women. The methods were moderately correlated. Both measures of arterial stiffness were independently associated with fasting glycaemia in men, but significant only for SC-PWV in women, after full adjustment. Further studies are needed for prediction of cardiovascular endpoints comparing the methods.}},
  author       = {{Nilsson, Peter and Johansson, Madeleine}},
  issn         = {{1473-5598}},
  keywords     = {{Aortic stiffness; vascular ageing; Population; Carotid-femoral pulse wave velocity}},
  language     = {{eng}},
  month        = {{05}},
  note         = {{Conference Abstract}},
  number       = {{Suppl 1}},
  pages        = {{149--149}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Journal of Hypertension}},
  title        = {{Correlation between carotid-femoral pulse wave velocity (PWV) at one measurement and 24-hour PWV in men and women assessed by two different methods in a population-based study}},
  url          = {{http://dx.doi.org/10.1097/01.hjh.0001020852.04644.41}},
  doi          = {{10.1097/01.hjh.0001020852.04644.41}},
  volume       = {{42}},
  year         = {{2024}},
}