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Stable refraction and visual acuity in diabetic patients with variable glucose levels under routine care.

Agardh, Elisabet LU ; Hellgren, Karl-Johan LU and Bengtsson, Boel LU (2011) In Acta Ophthalmologica 89. p.107-110
Abstract
Abstract. Purpose: To investigate how refraction and visual acuity may vary in patients with diabetes under routine care. Methods: Fifty-three eyes of 53 patients with various degrees of diabetic retinopathy were examined prospectively on four different occasions within a month. Refraction, best-corrected visual acuity (expressed as logMAR score) and blood glucose were measured on each occasion. Intraindividual variability was calculated as the range between the highest and lowest measurements. Associations between blood glucose levels and each of the other variables were tested by linear regression analysis for each patient. Results: Refraction was completely stable in 43 patients and changed only slightly in 10, in whom the mean... (More)
Abstract. Purpose: To investigate how refraction and visual acuity may vary in patients with diabetes under routine care. Methods: Fifty-three eyes of 53 patients with various degrees of diabetic retinopathy were examined prospectively on four different occasions within a month. Refraction, best-corrected visual acuity (expressed as logMAR score) and blood glucose were measured on each occasion. Intraindividual variability was calculated as the range between the highest and lowest measurements. Associations between blood glucose levels and each of the other variables were tested by linear regression analysis for each patient. Results: Refraction was completely stable in 43 patients and changed only slightly in 10, in whom the mean intraindividual variability of the spherical equivalent was 0.4 dioptres. Visual acuity test results were also highly reproducible. Mean intraindividual variability in visual acuity was 0.08 logMAR. Mean haemoglobin A1c (HbA1c) was 7.3 +/- 1.5% but individual blood glucose levels ranged from 2.8 to > 22.2 mmol/l. Intraindividual variability ranged from 0.5 to 18.1 mmol/l, with a median of 6.0 mmol/l for the entire group. There were no associations between refraction or visual acuity and blood glucose levels or inter- or intraindividual glucose variations. Conclusion: Refraction and visual acuity test results were highly reproducible and stable in patients with reasonably well controlled diabetes but variable blood glucose levels under routine care. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Ophthalmologica
volume
89
pages
107 - 110
publisher
Wiley-Blackwell
external identifiers
  • wos:000287664700028
  • pmid:19843017
  • scopus:79952241022
  • pmid:19843017
ISSN
1755-3768
DOI
10.1111/j.1755-3768.2009.01664.x
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Unit on Vascular Diabetic Complications (013241510), Ophthalmology (Lund) (013043000), Department of Clinical Sciences, Malmö (013240000)
id
65579d11-17d6-4f82-a966-75579fbb66e4 (old id 1500171)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/19843017?dopt=Abstract
date added to LUP
2016-04-04 07:31:13
date last changed
2022-01-29 02:16:38
@article{65579d11-17d6-4f82-a966-75579fbb66e4,
  abstract     = {{Abstract. Purpose: To investigate how refraction and visual acuity may vary in patients with diabetes under routine care. Methods: Fifty-three eyes of 53 patients with various degrees of diabetic retinopathy were examined prospectively on four different occasions within a month. Refraction, best-corrected visual acuity (expressed as logMAR score) and blood glucose were measured on each occasion. Intraindividual variability was calculated as the range between the highest and lowest measurements. Associations between blood glucose levels and each of the other variables were tested by linear regression analysis for each patient. Results: Refraction was completely stable in 43 patients and changed only slightly in 10, in whom the mean intraindividual variability of the spherical equivalent was 0.4 dioptres. Visual acuity test results were also highly reproducible. Mean intraindividual variability in visual acuity was 0.08 logMAR. Mean haemoglobin A1c (HbA1c) was 7.3 +/- 1.5% but individual blood glucose levels ranged from 2.8 to > 22.2 mmol/l. Intraindividual variability ranged from 0.5 to 18.1 mmol/l, with a median of 6.0 mmol/l for the entire group. There were no associations between refraction or visual acuity and blood glucose levels or inter- or intraindividual glucose variations. Conclusion: Refraction and visual acuity test results were highly reproducible and stable in patients with reasonably well controlled diabetes but variable blood glucose levels under routine care.}},
  author       = {{Agardh, Elisabet and Hellgren, Karl-Johan and Bengtsson, Boel}},
  issn         = {{1755-3768}},
  language     = {{eng}},
  pages        = {{107--110}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Ophthalmologica}},
  title        = {{Stable refraction and visual acuity in diabetic patients with variable glucose levels under routine care.}},
  url          = {{http://dx.doi.org/10.1111/j.1755-3768.2009.01664.x}},
  doi          = {{10.1111/j.1755-3768.2009.01664.x}},
  volume       = {{89}},
  year         = {{2011}},
}