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Attovial-based antibody nanoarrays.

Ellmark, Peter LU ; Ghatnekar-Nilsson, Sara LU ; Meister, André; Heinzelmann, Harry; Montelius, Lars LU ; Wingren, Christer LU and Borrebaeck, Carl LU (2009) In Proteomics 9(24). p.5406-5413
Abstract
Antibody array-based technology is a powerful emerging tool in proteomics, but to enable global proteome analysis, antibody array layouts with even higher density has to be developed. To this end, we have further developed the first generation of a nanoarray platform, based on attoliter sized vials, attovials, which we have characterized and used for the detection of complement factor C1q in human serum samples. Finally, we demonstrated proof-of-concept for individual functionalisation of the attovials with a recombinant antibody.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Proteomics
volume
9
issue
24
pages
5406 - 5413
publisher
John Wiley & Sons
external identifiers
  • wos:000273515000003
  • pmid:19798667
  • scopus:73149108854
ISSN
1615-9861
DOI
10.1002/pmic.200800962
language
English
LU publication?
yes
id
47096b06-b463-413a-a954-c80f31d5fd18 (old id 1500753)
date added to LUP
2009-12-01 10:26:25
date last changed
2017-02-12 03:24:29
@article{47096b06-b463-413a-a954-c80f31d5fd18,
  abstract     = {Antibody array-based technology is a powerful emerging tool in proteomics, but to enable global proteome analysis, antibody array layouts with even higher density has to be developed. To this end, we have further developed the first generation of a nanoarray platform, based on attoliter sized vials, attovials, which we have characterized and used for the detection of complement factor C1q in human serum samples. Finally, we demonstrated proof-of-concept for individual functionalisation of the attovials with a recombinant antibody.},
  author       = {Ellmark, Peter and Ghatnekar-Nilsson, Sara and Meister, André and Heinzelmann, Harry and Montelius, Lars and Wingren, Christer and Borrebaeck, Carl},
  issn         = {1615-9861},
  language     = {eng},
  number       = {24},
  pages        = {5406--5413},
  publisher    = {John Wiley & Sons},
  series       = {Proteomics},
  title        = {Attovial-based antibody nanoarrays.},
  url          = {http://dx.doi.org/10.1002/pmic.200800962},
  volume       = {9},
  year         = {2009},
}